Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.006G238900.2 |
Family | GT47 |
Protein Properties | Length: 664 Molecular Weight: 74611.6 Isoelectric Point: 7.7016 |
Chromosome | Chromosome/Scaffold: 06 Start: 24806236 End: 24810497 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 332 | 614 | 0 |
EKMLKVYVYQDGEKPIFHQPILDGIYASEGWFMKHMEANENFVTKDPGKAHLFYLPFSSRLLELTLYVRHSHSRTNLIEYMRNYAGMIAAKYHFWNRTGG ADHFVAACHDWAPAETRGPLLNCIRALCNADIEVGFSIGKDVSLPETYVRSAQNPLKNLEGNPPSQRPILAFFAGNMHGYVRPVLLDYWGNKDPDMKIFG PMPHVKGNTNYIQHMKSSKFCICPRGHEVNSPRIVEAIFLECVPVIISDNFVPPFFEVLDWESFAVIVLEKDIPNLKNILVSI |
Full Sequence |
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Protein Sequence Length: 664 Download |
MDQGYQLLCL AKARRLLFLV GATVAIVIVV QYLEFPSSRV LVSLFSAVNT RSFMSRNSST 60 GSEALGNMTL SNGLNTTNTG ILHETTDSDE ASDDKKETAE VNKSEEKEGS PNNSNASESK 120 RGSSDSFGLV SNETISDDLA NQDKNSTLNT INGSEEEKAM APDASYINVD KDIAPISGRN 180 KSSDADPGYP SSAPPMMNTF SNKTFSTDEN SSPMIFESSN TTSMRKDTAG ALKRDENSGL 240 LPNNYSMSTS GSFSSKVTAA KRKTSKKPPS RVISIHQMNE LLRQSHASSS SVEMLFAKSQ 300 IENAPLIKNE TRLYAPIYRN VSMFRRSYEL MEKMLKVYVY QDGEKPIFHQ PILDGIYASE 360 GWFMKHMEAN ENFVTKDPGK AHLFYLPFSS RLLELTLYVR HSHSRTNLIE YMRNYAGMIA 420 AKYHFWNRTG GADHFVAACH DWAPAETRGP LLNCIRALCN ADIEVGFSIG KDVSLPETYV 480 RSAQNPLKNL EGNPPSQRPI LAFFAGNMHG YVRPVLLDYW GNKDPDMKIF GPMPHVKGNT 540 NYIQHMKSSK FCICPRGHEV NSPRIVEAIF LECVPVIISD NFVPPFFEVL DWESFAVIVL 600 EKDIPNLKNI LVSISEEKYI EMHKRVKKVQ QHFLWHSKPE KYDLFHMILH SVWYNRIFRI 660 RPA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-68 | 331 | 614 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 5 | 659 | 716 | 1390 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 1 | 661 | 1 | 667 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002283936.1 | 0 | 268 | 662 | 2 | 409 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309546.1 | 0 | 247 | 663 | 1 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516500.1 | 0 | 227 | 663 | 12 | 456 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |