Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.006G239000.1 |
Family | GT47 |
Protein Properties | Length: 706 Molecular Weight: 79944 Isoelectric Point: 7.9381 |
Chromosome | Chromosome/Scaffold: 06 Start: 24812676 End: 24815799 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 374 | 656 | 0 |
ILKVYIYKEGEMPIFHQPLLNGIYASEGWFMKLLEGNKKFVTKDSKKAHLFYLPFSSRYLEIRLYVPNSHSHKNLIEYLKKYLDMISEKYPFWNRTQGAD HFLAACHDWAPSETRQHMANCIRALCNSDAKEDFVYGKDASLPETYVLTQENPLRDLGGNRASKRSILAFFAGSMHGYLRPILLQHWENKDPDMKIFGRL PKVKGRGKMNYARYMKSSKYCICAKGYEVNSPRVVEAIFYECVPVIISDNFVPPFLEVLNWESFAVFVLEKDIPNLKKILLSI |
Full Sequence |
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Protein Sequence Length: 706 Download |
MGNEFRYPFT IEIWKLLWFI GLAVAVVLTF QHFELPYGNI ISSLSSARKD LGAGNSNLLT 60 HAASSTPEMV SNTTQSNGLN TTAISPDRAQ ETDNSHGTET PANVNNDVVP ERSRGLNESS 120 LIDSRGKESS PEQLVDTNTN STSYVHNGVV SEGISGLNKS SGIDNHGKES KPEQLVMEPV 180 NSLGNGSAPQ ETERSLSRED VTSISENIGA SDARIAPIAP ELLPVDSPPN ITLQMNAEPS 240 TIAHIVPIES NTSKVDKDAA PSLENDGKTG DQKKDLTLLH NNPSVTSFPE VKKEPQTPSL 300 EVVSISEMKN LQLQRWSSPN SRRPRWPSVV DQELLNAKSQ IQNAPIVEND PVLYAPLYWN 360 ISMFKKSYEL MEDILKVYIY KEGEMPIFHQ PLLNGIYASE GWFMKLLEGN KKFVTKDSKK 420 AHLFYLPFSS RYLEIRLYVP NSHSHKNLIE YLKKYLDMIS EKYPFWNRTQ GADHFLAACH 480 DWAPSETRQH MANCIRALCN SDAKEDFVYG KDASLPETYV LTQENPLRDL GGNRASKRSI 540 LAFFAGSMHG YLRPILLQHW ENKDPDMKIF GRLPKVKGRG KMNYARYMKS SKYCICAKGY 600 EVNSPRVVEA IFYECVPVII SDNFVPPFLE VLNWESFAVF VLEKDIPNLK KILLSIPAKK 660 YRRMQMRVKR VQQHFLWHAR PVKYDVFHMI LHSIWYNRVF QMQPR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-67 | 375 | 656 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_197954.1 | 0 | 1 | 702 | 1 | 652 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 705 | 1 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 235 | 705 | 1 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 308 | 705 | 1 | 398 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516499.1 | 0 | 1 | 705 | 1 | 601 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |