Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.007G058400.1 |
Family | GT47 |
Protein Properties | Length: 427 Molecular Weight: 48844.8 Isoelectric Point: 8.2642 |
Chromosome | Chromosome/Scaffold: 07 Start: 6272709 End: 6277215 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 103 | 379 | 0 |
HNFKIYIYPDGDPNTFYQTPRKLTGKYASEGYFFQNIRESRFRTLDPDQAHLFFIPISCHKMRGKGTSYENMTVIVENYVESLIAKYSYWNRTLGADHFF VTCHDVGVRATEGVPFLIKNAIRVVCSPSYDVGFIPHKDVALPQVLQPFALPAGGNDVENRTTLGFWAGHRNSRIRVILARVWENDTELDISSNRINRAT GHLVYQKRFYGTKFCICPGGSQVNSARIADSIHYGCVPVILSNYYDLPFNDILDWHKFSVILKEQDVYQLKQILKDI |
Full Sequence |
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Protein Sequence Length: 427 Download |
MTAGKLYQQL QQQQQVQLSM CSLKGSLLTL AILTLISFTY LSFNSLHSSP SPSISASSVS 60 LLPATETTTK TVVVDVGDGE NDEISDLYHS PRVFKLNYEE MEHNFKIYIY PDGDPNTFYQ 120 TPRKLTGKYA SEGYFFQNIR ESRFRTLDPD QAHLFFIPIS CHKMRGKGTS YENMTVIVEN 180 YVESLIAKYS YWNRTLGADH FFVTCHDVGV RATEGVPFLI KNAIRVVCSP SYDVGFIPHK 240 DVALPQVLQP FALPAGGNDV ENRTTLGFWA GHRNSRIRVI LARVWENDTE LDISSNRINR 300 ATGHLVYQKR FYGTKFCICP GGSQVNSARI ADSIHYGCVP VILSNYYDLP FNDILDWHKF 360 SVILKEQDVY QLKQILKDIP DNQFVSLHKN LIKVQKHFQW NSPPIKNDAF HMVMYDLWLR 420 RHVIKY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-56 | 101 | 379 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195517.1 | 0 | 20 | 426 | 19 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 12 | 426 | 8 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303415.1 | 0 | 101 | 426 | 1 | 326 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002307304.1 | 0 | 20 | 426 | 1 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 1 | 426 | 1 | 406 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |