Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.007G116800.1 |
Family | GT47 |
Protein Properties | Length: 421 Molecular Weight: 49470.2 Isoelectric Point: 8.8891 |
Chromosome | Chromosome/Scaffold: 07 Start: 13746017 End: 13748454 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 83 | 373 | 0 |
ENDFKVFVYPGRDPTTCYDPRDKLKRKYASEHYFLKNLIPSSFFTDDPTVAHLFLIPLSCKKTGGREEKDIENYVKSLISSYPYWNRTLGADHFYFSCHG IDSGTIEEVPLLMKNVIRLVCSPSYDSKYIPHKDISLPQTLELSLHDGDDVWSRSTVMSRPLMIYPEMMLPRRTKLGFWAGSLNSDVRKNLQVFYKGAPE FNFHFFDKMKKAAILDAYENELYGSKFCICPRGNNHVGSVCLTESMTFGCVPVILHDYYDFPFNDVLDWNNFSVILKEEHVPDLEKILKGI |
Full Sequence |
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Protein Sequence Length: 421 Download |
MMRPYANPRP INIWTARRNI KKIIPVTLGL VFIVTQIIQL QRSPLFREKD SLPDEVFRTR 60 KGNSIGSIYH REDFFLPNYA TMENDFKVFV YPGRDPTTCY DPRDKLKRKY ASEHYFLKNL 120 IPSSFFTDDP TVAHLFLIPL SCKKTGGREE KDIENYVKSL ISSYPYWNRT LGADHFYFSC 180 HGIDSGTIEE VPLLMKNVIR LVCSPSYDSK YIPHKDISLP QTLELSLHDG DDVWSRSTVM 240 SRPLMIYPEM MLPRRTKLGF WAGSLNSDVR KNLQVFYKGA PEFNFHFFDK MKKAAILDAY 300 ENELYGSKFC ICPRGNNHVG SVCLTESMTF GCVPVILHDY YDFPFNDVLD WNNFSVILKE 360 EHVPDLEKIL KGIPEENYKK MHQNLLQVRK HFQWNSLPVK YDLFRMIMYE LWLRRHIIKY 420 * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-45 | 82 | 373 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002266299.1 | 0 | 68 | 420 | 77 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268836.1 | 0 | 63 | 420 | 73 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 63 | 420 | 62 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002309859.1 | 0 | 1 | 420 | 1 | 420 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321656.1 | 0 | 63 | 420 | 42 | 407 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |