y
Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.007G117600.1 |
Family | GT47 |
Protein Properties | Length: 385 Molecular Weight: 44673.2 Isoelectric Point: 6.7426 |
Chromosome | Chromosome/Scaffold: 07 Start: 13783777 End: 13786422 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 62 | 334 | 0 |
ERKFKIFVYPHNTSSCSNPRTLDGEYGNEGLFYLNLNLSRFLTKDPEKAHLFLIPISCHSLPAGRSEDERAIAVEDFVKSLISKYPYWNRTLGADHFFVT CVDINVTATARIANLMKNSIKVMCTPSYNDEYVPHKDVSLPQRVPPLALTPAGNNITNRITLAFWRGLNNSDIRQKLLEAWENDLELFIQKGRKPSLEQG DLVHHEAFNNSKYCICPGGPELDRTIALAIHYGCVPVIMSDYYDLPFKDILDWRKFSIILEESQVYYLREHLK |
Full Sequence |
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Protein Sequence Length: 385 Download |
MKNLKRGGLA CFFVIVSICF FIYPPGFPPF QGSFQAYAQE AGFFGEVFHV PEAFDPDYEE 60 MERKFKIFVY PHNTSSCSNP RTLDGEYGNE GLFYLNLNLS RFLTKDPEKA HLFLIPISCH 120 SLPAGRSEDE RAIAVEDFVK SLISKYPYWN RTLGADHFFV TCVDINVTAT ARIANLMKNS 180 IKVMCTPSYN DEYVPHKDVS LPQRVPPLAL TPAGNNITNR ITLAFWRGLN NSDIRQKLLE 240 AWENDLELFI QKGRKPSLEQ GDLVHHEAFN NSKYCICPGG PELDRTIALA IHYGCVPVIM 300 SDYYDLPFKD ILDWRKFSII LEESQVYYLR EHLKEMLEHE YRAMQTNTVM VRKHFQWNLV 360 PAKYDAFHMT MYDLWLRNHF TKYY* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-48 | 61 | 336 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 46 | 383 | 69 | 409 | unknown [Glycine max] |
RefSeq | XP_002266299.1 | 0 | 39 | 383 | 69 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268836.1 | 0 | 34 | 383 | 65 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 45 | 383 | 65 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002309856.1 | 0 | 61 | 384 | 1 | 326 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |