Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.008G034500.1 |
Family | GT47 |
Protein Properties | Length: 440 Molecular Weight: 50634 Isoelectric Point: 9.1313 |
Chromosome | Chromosome/Scaffold: 08 Start: 1903259 End: 1906518 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 57 | 372 | 0 |
LKVYMYDLPRRFNIGMMQWKKGGGDDTPVRTAEELPRWPVNVGVRKQHSVEYWLMASLLGSGGEGEEREAVRVLDPEIAEAYFVPFFSSLSFNTHGRNMT DPETEKDRQLQVDLIDFLQKSKYWQRSGGRDHVIPMTHPNAFRFLRQLVNASILIVADFGRYPKSLSTLSKDVVSPYVHNVDSFKDDDLLDPFESRKTLL FFRGNTVRKDKGKVRAKLEKILAGYDDVRYERSSPTAEAIQASTQGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDLIELPYEDEIDYSQFSIFF SINEAIQPDYLVNQLR |
Full Sequence |
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Protein Sequence Length: 440 Download |
MYGKAIVSLA FIILLLISFS LFIGTVDIRS YFFASPDGAH NLPCTPTHTQ SSPSVPLKVY 60 MYDLPRRFNI GMMQWKKGGG DDTPVRTAEE LPRWPVNVGV RKQHSVEYWL MASLLGSGGE 120 GEEREAVRVL DPEIAEAYFV PFFSSLSFNT HGRNMTDPET EKDRQLQVDL IDFLQKSKYW 180 QRSGGRDHVI PMTHPNAFRF LRQLVNASIL IVADFGRYPK SLSTLSKDVV SPYVHNVDSF 240 KDDDLLDPFE SRKTLLFFRG NTVRKDKGKV RAKLEKILAG YDDVRYERSS PTAEAIQAST 300 QGMRSSKFCL HPAGDTPSSC RLFDAIVSHC VPVIVSDLIE LPYEDEIDYS QFSIFFSINE 360 AIQPDYLVNQ LRKFPKDRWI EMWRQLKKIS HHFEFQYPPV KEDAVNLLWR QVKNKLPGAQ 420 LAVHRNHRLK VPDWWQRRR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-66 | 53 | 374 | 330 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 1 | 416 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 1 | 435 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 27 | 439 | 27 | 430 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 56 | 435 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 1 | 438 | 1 | 434 | catalytic, putative [Ricinus communis] |