| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.008G060500.1 |
| Family | GT47 |
| Protein Properties | Length: 346 Molecular Weight: 39342.1 Isoelectric Point: 7.7884 |
| Chromosome | Chromosome/Scaffold: 08 Start: 3652684 End: 3654227 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 43 | 277 | 7.9e-39 |
| SFKIYIYTPSKPFSFSSPTESLFFTSLQASPFVTQNPEEAHLFFVPFASNLSTRSIARFIRDLRMEFPYWNRTLGADHFYVSCAGLGYESDRNLVELKKN SVQISCFPVPEGKFVPHKDISLPPLARITRASHAPGNRTVRYLVRHGGVKDSKLANELRNDSDFLMESEPSNEMTLVERLGSSMFCLFEDGADISGIGEA LRFGCVPVMVTDRPMQDLPLMDVLSWQKIAVFVGS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 346 Download |
| MSTIIYFLCL SLLTSVSKSI NDSTSLYLSP TIFFPNYQNM LNSFKIYIYT PSKPFSFSSP 60 TESLFFTSLQ ASPFVTQNPE EAHLFFVPFA SNLSTRSIAR FIRDLRMEFP YWNRTLGADH 120 FYVSCAGLGY ESDRNLVELK KNSVQISCFP VPEGKFVPHK DISLPPLARI TRASHAPGNR 180 TVRYLVRHGG VKDSKLANEL RNDSDFLMES EPSNEMTLVE RLGSSMFCLF EDGADISGIG 240 EALRFGCVPV MVTDRPMQDL PLMDVLSWQK IAVFVGSGGG IKEMKRVLDR TCKDDECEGT 300 RRLGVAASQH FGWNEIPQPY DSFYMVVYQL WLRRHTIRYP RREFV* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-26 | 65 | 275 | 244 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002282317.1 | 0 | 1 | 345 | 6 | 360 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002307304.1 | 0 | 21 | 339 | 62 | 406 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002311191.1 | 0 | 1 | 345 | 1 | 345 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 1 | 345 | 1 | 339 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 30 | 345 | 32 | 337 | conserved hypothetical protein [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
