| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.012G091600.1 |
| Family | GT47 |
| Protein Properties | Length: 246 Molecular Weight: 28306.3 Isoelectric Point: 7.2792 |
| Chromosome | Chromosome/Scaffold: 12 Start: 11860755 End: 11862372 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT47 | 58 | 222 | 2.4e-32 |
| EKDFKVFVYPGGNPGTCYHSTNNTLKSNHASEHYFFMNLRDSPFLTKNPQEAHLFFIFISCLPLSDEEPLPGYRERVIKRYVKGLISTYPYWNRTLGADH FFVSCHNIGSTATKEIPFLLKNAIRLVCSPSYDSNYIPQKDVALPQILELSLPPDGDDMWNRNLM | |||
| Full Sequence |
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| Protein Sequence Length: 246 Download |
| EYSQRIYVRG HRFGRSLYPV PVQPVPLLGD LIQYTVQDST DDIYHSRAFF LLNHEAMEKD 60 FKVFVYPGGN PGTCYHSTNN TLKSNHASEH YFFMNLRDSP FLTKNPQEAH LFFIFISCLP 120 LSDEEPLPGY RERVIKRYVK GLISTYPYWN RTLGADHFFV SCHNIGSTAT KEIPFLLKNA 180 IRLVCSPSYD SNYIPQKDVA LPQILELSLP PDGDDMWNRN LMQLARSTVE SRPLLLSQEM 240 INPPR* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-22 | 57 | 214 | 166 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002266299.1 | 0 | 24 | 222 | 55 | 256 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309859.1 | 0 | 38 | 245 | 63 | 255 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002318097.1 | 0 | 27 | 245 | 25 | 243 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002321656.1 | 0 | 24 | 245 | 28 | 242 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522880.1 | 0 | 38 | 222 | 62 | 246 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| JG847451 | 182 | 42 | 222 | 0 |
| FD499965 | 181 | 43 | 222 | 0 |
| DV151107 | 188 | 29 | 215 | 0 |
| ES829766 | 182 | 42 | 222 | 0 |
| JG627253 | 177 | 41 | 216 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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