Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.012G109200.1 |
Family | GT47 |
Protein Properties | Length: 404 Molecular Weight: 46071.1 Isoelectric Point: 6.3499 |
Chromosome | Chromosome/Scaffold: 12 Start: 13200704 End: 13204887 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 50 | 331 | 0 |
RLKVFVYELPRKYNKKILQKDPRCLTHMFAAEIFMHRFLLSSPVRTLNPDEADWFYTPVYTTCDLTTNGLPLPFKSPRMMRSAIQLISSNWPYWNRTEGA DHFFVVPHDFGACFHYQRRLLKEEFFPCSNVCLKDGSITVPPYAPPQKMQTHLIPEKTPRSIFVYFRGLFYDVGNDPEGGYYARGARAAVWENFKDNPLF DISTEHPATYYEDMQRAVFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEEIGVYVDEEDVPNLDTILTSI |
Full Sequence |
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Protein Sequence Length: 404 Download |
MEIWKWVFVG VLWYAGFVLS TGAVELGRSQ HTERISGSAG DVLEDDPVGR LKVFVYELPR 60 KYNKKILQKD PRCLTHMFAA EIFMHRFLLS SPVRTLNPDE ADWFYTPVYT TCDLTTNGLP 120 LPFKSPRMMR SAIQLISSNW PYWNRTEGAD HFFVVPHDFG ACFHYQRRLL KEEFFPCSNV 180 CLKDGSITVP PYAPPQKMQT HLIPEKTPRS IFVYFRGLFY DVGNDPEGGY YARGARAAVW 240 ENFKDNPLFD ISTEHPATYY EDMQRAVFCL CPLGWAPWSP RLVEAVIFGC IPVIIADDIV 300 LPFADAIPWE EIGVYVDEED VPNLDTILTS IPPEVILRKQ RLLANPSMKQ AMLFPQPAQP 360 GDAFHQVLNG LARKLPHDRS VYLRPGEKIL NWTAGPVGDL KPW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-78 | 50 | 331 | 300 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM64940.1 | 0 | 20 | 403 | 18 | 415 | unknown [Arabidopsis thaliana] |
RefSeq | NP_568941.1 | 0 | 20 | 403 | 18 | 415 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002284685.1 | 0 | 1 | 403 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318180.1 | 0 | 1 | 403 | 1 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 1 | 403 | 1 | 417 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |