Basic Information | |
---|---|
Species | Populus trichocarpa |
Cazyme ID | Potri.012G124600.1 |
Family | GT47 |
Protein Properties | Length: 480 Molecular Weight: 54670.6 Isoelectric Point: 8.6854 |
Chromosome | Chromosome/Scaffold: 12 Start: 14354997 End: 14358305 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 91 | 403 | 0 |
ERKVRVFMHDLPKKFTTGIIENHGLARGHSNLSKVSYPGHQHMGEWYLYSDLSRPESDRVGSPVVKVNDPEEADLFYVPVFSSLSLTVNPVQVGKVPVSD PVYSDEKMQDELVEWLEKQEYWRRNNGRDHVLFAGDPNALYRVLDRVKNAVLLLSDFGRVRSDQGSLVKDVIVPYAHRINVYNGDIGVDERKTLLFFMGN RYRKDGGKIRDMLFQLLEKEEDVLISHGTQSRESRRTATLGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPLIVSDSIELPFEDVIDYRKIAIFVDTESS LKPGYLVKLLRAV |
Full Sequence |
---|
Protein Sequence Length: 480 Download |
MIEKLLKTKK PKSPNSSKFP QIMTRKSSLL KRTLILSAFT VLIIYVSFNT FLSYFTTTAT 60 AGVSATTSSI FAEQISRENF QDFPVKATGN ERKVRVFMHD LPKKFTTGII ENHGLARGHS 120 NLSKVSYPGH QHMGEWYLYS DLSRPESDRV GSPVVKVNDP EEADLFYVPV FSSLSLTVNP 180 VQVGKVPVSD PVYSDEKMQD ELVEWLEKQE YWRRNNGRDH VLFAGDPNAL YRVLDRVKNA 240 VLLLSDFGRV RSDQGSLVKD VIVPYAHRIN VYNGDIGVDE RKTLLFFMGN RYRKDGGKIR 300 DMLFQLLEKE EDVLISHGTQ SRESRRTATL GMHTSKFCLN PAGDTPSACR LFDSIVSLCV 360 PLIVSDSIEL PFEDVIDYRK IAIFVDTESS LKPGYLVKLL RAVSTERILE YQKEMREVKR 420 YFEYSDPNGT VNEIWREIGQ KLPLIQLMIN REKRLVKRDS TEPDCSCLCT NQSTLFTSL* 480 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-76 | 92 | 403 | 323 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 86 | 479 | 64 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_850241.1 | 0 | 23 | 479 | 1 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 98 | 479 | 1 | 382 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 23 | 479 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 23 | 479 | 1 | 452 | catalytic, putative [Ricinus communis] |