| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.012G131400.1 |
| Family | GH29 |
| Protein Properties | Length: 486 Molecular Weight: 54941.4 Isoelectric Point: 6.9534 |
| Chromosome | Chromosome/Scaffold: 12 Start: 14785281 End: 14788032 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 14 | 338 | 0 |
| LQVSKVVISRREVTTPPLPILPLPSSSQLKWQERELIMFLHFGVNTFTDSEWGTGHENPAIFNPVGLNASQWVNVAAEAGFSLMILTAKHHDGFCLWPSK YTDHSVASSPWKNGRGDVVQELVIAARAHEGIDVGLYLSPWDRHDKRYGHDLQYNEYYLAQLQELLNKYGSVREIWFDGAKGSNVPNMSYYFSDWFSMVK ELQTSINIFSDAGPDVRWVGNEMGFAGSTCWSTINRTSLSIGNGSIVDYLNTGDSKGTDWLPAECDVSIRKGWFWHKSESPKRLSELLDIYYKSVGRNCV LLFNVPPNTTGLISENDVQRLKEFR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 486 Download |
| MAKLWCLLTI ITLLQVSKVV ISRREVTTPP LPILPLPSSS QLKWQERELI MFLHFGVNTF 60 TDSEWGTGHE NPAIFNPVGL NASQWVNVAA EAGFSLMILT AKHHDGFCLW PSKYTDHSVA 120 SSPWKNGRGD VVQELVIAAR AHEGIDVGLY LSPWDRHDKR YGHDLQYNEY YLAQLQELLN 180 KYGSVREIWF DGAKGSNVPN MSYYFSDWFS MVKELQTSIN IFSDAGPDVR WVGNEMGFAG 240 STCWSTINRT SLSIGNGSIV DYLNTGDSKG TDWLPAECDV SIRKGWFWHK SESPKRLSEL 300 LDIYYKSVGR NCVLLFNVPP NTTGLISEND VQRLKEFRGA IDTIFSTNLA ESCFVRASSQ 360 RGGKDGDFGP ENVLDGDHLW TYWAPKDEES EDNWIEFKCI DKLRFNVIRI QEAIGLGQRI 420 KQHEVYVDGR KVAKGTTVGH KRLHRLEKGV VKGHIVSIKI LKSRAVPLMS SIGLHYDPFW 480 HPNET* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 1.0e-28 | 44 | 337 | 332 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 7.0e-32 | 44 | 337 | 337 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 8.0e-58 | 41 | 474 | 447 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 39 | 482 | 21 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 26 | 485 | 5 | 464 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 485 | 1 | 485 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 483 | 1 | 484 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 482 | 1 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 32 | 475 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 32 | 475 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 37 | 470 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 37 | 470 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 37 | 470 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
