Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.013G116200.1 |
Family | GT47 |
Protein Properties | Length: 482 Molecular Weight: 54682.9 Isoelectric Point: 9.0503 |
Chromosome | Chromosome/Scaffold: 13 Start: 12976652 End: 12979494 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 59 | 406 | 0 |
AFIKVYVADLPRSLNYGLLDQYWSSSMPDARISSDPDHQIRPRPIKNLKFPDYPENPLIKQYSAEYWITGDLMTSEKLKSRSFAKRVFDFNEADVVFVPF FATLSAEMELAKGKGSFRRKEGNEDYQRQKEVVDFVRNSEAWKRSGGKDHVFVLTDPVAMWHVRAEIAPAILLVVDFGGWYRLDSKSSNGSSSDMIRHTQ VSLLKDVIVPYTHLLPRFQFSENKKRNTLLYFKGAKHRHRGGIVRENLWDLLVNEPGVIMEEGFPNATGRELSIRGMRTSEFCLHPAGDTPTSCRLFDAI QSLCIPVIVSDNIELPFEGILDYTEFSVFVAGDDALKPTWLMDHLRSI |
Full Sequence |
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Protein Sequence Length: 482 Download |
MPPPPPKTTT TTTTPLPCSN PTLFLAFTLL TFLSLSLFFI SNKISSFPNP QNTLQISQAF 60 IKVYVADLPR SLNYGLLDQY WSSSMPDARI SSDPDHQIRP RPIKNLKFPD YPENPLIKQY 120 SAEYWITGDL MTSEKLKSRS FAKRVFDFNE ADVVFVPFFA TLSAEMELAK GKGSFRRKEG 180 NEDYQRQKEV VDFVRNSEAW KRSGGKDHVF VLTDPVAMWH VRAEIAPAIL LVVDFGGWYR 240 LDSKSSNGSS SDMIRHTQVS LLKDVIVPYT HLLPRFQFSE NKKRNTLLYF KGAKHRHRGG 300 IVRENLWDLL VNEPGVIMEE GFPNATGREL SIRGMRTSEF CLHPAGDTPT SCRLFDAIQS 360 LCIPVIVSDN IELPFEGILD YTEFSVFVAG DDALKPTWLM DHLRSISEKQ KEELRRNMAK 420 IQLIYQYENG HPGGIGPISP NGAVNHIWKK IHEKLPVIKE AIVREKRKPP GVSIPLRCHC 480 T* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-59 | 57 | 406 | 362 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 41 | 480 | 37 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 10 | 481 | 9 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 18 | 481 | 13 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 33 | 481 | 1 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 41 | 481 | 35 | 478 | catalytic, putative [Ricinus communis] |