y
Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.014G053200.1 |
Family | GT57 |
Protein Properties | Length: 534 Molecular Weight: 60849.2 Isoelectric Point: 8.8276 |
Chromosome | Chromosome/Scaffold: 14 Start: 4195388 End: 4199217 |
Description | ALG6, ALG8 glycosyltransferase family |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT57 | 25 | 525 | 0 |
STCVKLLLIPSYHSTDFEVHRNWLAITHSLPLDQWYIDKTSPWTLDYPPFFAYFEYIISFFAHLVDPKIVDLEKGLDYKAESVVLFQRLSVIVCDLVLLY GVYRLSKNFSMGFKERVLMWVLVVWSPGLVIVDHMHFQYNGFLLGLLMMSISYLMEGRDLMGGFIFAVLLCFKHLFAVAAPVYFVYLLRHYCWKGFVKGF WRISVLGAVVVAVFAAAYGPFVYLGQMQQVISRMFPFGRGLCHAYWAPNFWVFYIILDKGLAFLLKKLGLNIPVPAASFTGGLVGDSSPFAILPQVTPLT TFIMVLLALSPCLIKVWKNPQPRSVARWIAYAYMCGFLFGWHVHEKASLHFVIPLAIVAGNSLEDARHYFLLSIVSCYSLFPLLYEAQEYPIKVLLLLLH SVLMWQSFSALFTTDATAKAVVSAKKTDRQVGLKGSSSDVVEKGGFHIGWIGRCYLFGLLAVEIWGQFLHPYLLGDKLPFVPLLLISIYCALEIMYSWIW Q |
Full Sequence |
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Protein Sequence Length: 534 Download |
MEDQRKPEKN KSSTTSNLLW FFGVSTCVKL LLIPSYHSTD FEVHRNWLAI THSLPLDQWY 60 IDKTSPWTLD YPPFFAYFEY IISFFAHLVD PKIVDLEKGL DYKAESVVLF QRLSVIVCDL 120 VLLYGVYRLS KNFSMGFKER VLMWVLVVWS PGLVIVDHMH FQYNGFLLGL LMMSISYLME 180 GRDLMGGFIF AVLLCFKHLF AVAAPVYFVY LLRHYCWKGF VKGFWRISVL GAVVVAVFAA 240 AYGPFVYLGQ MQQVISRMFP FGRGLCHAYW APNFWVFYII LDKGLAFLLK KLGLNIPVPA 300 ASFTGGLVGD SSPFAILPQV TPLTTFIMVL LALSPCLIKV WKNPQPRSVA RWIAYAYMCG 360 FLFGWHVHEK ASLHFVIPLA IVAGNSLEDA RHYFLLSIVS CYSLFPLLYE AQEYPIKVLL 420 LLLHSVLMWQ SFSALFTTDA TAKAVVSAKK TDRQVGLKGS SSDVVEKGGF HIGWIGRCYL 480 FGLLAVEIWG QFLHPYLLGD KLPFVPLLLI SIYCALEIMY SWIWQLRQIM VST* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03155 | Alg6_Alg8 | 2.0e-101 | 23 | 524 | 515 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. |
Gene Ontology | |
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GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI16712.1 | 0 | 2 | 533 | 3 | 472 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_181994.5 | 0 | 8 | 531 | 2 | 506 | transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
Swiss-Prot | O80505 | 0 | 8 | 413 | 2 | 405 | ALG8_ARATH RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; AltName: Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase; AltName: Full=Asparagine-linked glycosylation protein 8 homolog |
RefSeq | XP_002269114.1 | 0 | 1 | 533 | 1 | 532 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002521523.1 | 0 | 1 | 533 | 1 | 493 | dolichyl glycosyltransferase, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
dolichyl-diphosphooligosaccharide biosynthesis | RXN-5471 | EC-2.4.1.265 | Dol-P-Glc:Glc1Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |