| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.014G096700.2 |
| Family | GH18 |
| Protein Properties | Length: 313 Molecular Weight: 35484.6 Isoelectric Point: 6.5175 |
| Chromosome | Chromosome/Scaffold: 14 Start: 7564251 End: 7568878 |
| Description | Glycosyl hydrolase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 63 | 303 | 5e-33 |
| LLKKKKLRDKAIDLIISECKEMEYDGIVLESWSRWAAYGILHDPEMRNKALQFIKQLGHAMHSVSSSRNGKQYLQLVYVIGPPYSEKLQPHDFGPEDLQS LSDDVDGFSFMTYDFSSPHNPGPNAPLKWIRFTLQILLGNSGARALANKIFLGINFYGNDFVISEGSEGGGAITGREYLSLLEKHKPELQWEKNSGEHFF LYVDDEHINHAVFYPSLMSISIRLEEARLQGVGISIWEIGQ | |||
| Full Sequence |
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| Protein Sequence Length: 313 Download |
| MAKRFTNKFT ILSPVWYDLK SQGTGLVLEG RHNADMGWIS ELRRNGNALV LPRVVLEAFP 60 KELLKKKKLR DKAIDLIISE CKEMEYDGIV LESWSRWAAY GILHDPEMRN KALQFIKQLG 120 HAMHSVSSSR NGKQYLQLVY VIGPPYSEKL QPHDFGPEDL QSLSDDVDGF SFMTYDFSSP 180 HNPGPNAPLK WIRFTLQILL GNSGARALAN KIFLGINFYG NDFVISEGSE GGGAITGREY 240 LSLLEKHKPE LQWEKNSGEH FFLYVDDEHI NHAVFYPSLM SISIRLEEAR LQGVGISIWE 300 IGQGLDYFFN LL* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00704 | Glyco_hydro_18 | 6.0e-10 | 70 | 303 | 254 | + Glycosyl hydrolases family 18. | ||
| COG3858 | COG3858 | 3.0e-19 | 70 | 312 | 252 | + Predicted glycosyl hydrolase [General function prediction only] | ||
| smart00636 | Glyco_18 | 2.0e-21 | 1 | 303 | 334 | + Glyco_18 domain. | ||
| cd02874 | GH18_CFLE_spore_hydrolase | 7.0e-23 | 70 | 303 | 246 | + Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. | ||
| cd02876 | GH18_SI-CLP | 1.0e-132 | 1 | 312 | 317 | + Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN82499.1 | 0 | 1 | 312 | 144 | 516 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI40499.1 | 0 | 1 | 312 | 123 | 435 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_192013.1 | 0 | 1 | 312 | 117 | 430 | glycosyl hydrolase family 18 protein [Arabidopsis thaliana] |
| RefSeq | XP_002320856.1 | 0 | 1 | 312 | 88 | 399 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523373.1 | 0 | 1 | 312 | 120 | 432 | chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3bxw_A | 0 | 1 | 312 | 95 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3bxw_B | 0 | 1 | 312 | 95 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3cz8_B | 0.0000001 | 172 | 295 | 180 | 304 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| PDB | 3cz8_A | 0.0000001 | 172 | 295 | 180 | 304 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CV229890 | 207 | 107 | 313 | 0 |
| EY666243 | 262 | 50 | 309 | 0 |
| EG658151 | 262 | 18 | 277 | 0 |
| CX667344 | 229 | 87 | 313 | 0 |
| EL360222 | 276 | 7 | 278 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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