y
Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.015G087900.1 |
Family | GT47 |
Protein Properties | Length: 408 Molecular Weight: 47250.7 Isoelectric Point: 7.9876 |
Chromosome | Chromosome/Scaffold: 15 Start: 11062723 End: 11065555 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 62 | 360 | 0 |
EKDLKVFVYPGGNPKTCYHSIDKKLKSNYASEHYFFMNLRNGSFLTENPDEAHLFFIPLSCQPMEDQDALPRYKEMVIQNYVRALTIKYPYWNRTLGADH FFVSCHGIGNRATAAFPFLLKNAIRLVCSPSYDSNYIPHKDVSLPQILELSFPPEGDGMWNDSTMESLPIQLSPVETHPSRTKLCFWAGSPNSEVRKNLR VHYKGLEEFEIHFVENVKRALVLDTFQKEIHRSKFCICPRGKTQVGGVCLAESMAFGCVPVIMSDYYDLPFNDILDWNAFSVILKEHDVPIMGEILKGI |
Full Sequence |
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Protein Sequence Length: 408 Download |
MPPLKALAAL VIFLGIASIL LQQRYWLPLS SKGKSTLYGL QQSTAGVHHS EEFFLLNYEA 60 MEKDLKVFVY PGGNPKTCYH SIDKKLKSNY ASEHYFFMNL RNGSFLTENP DEAHLFFIPL 120 SCQPMEDQDA LPRYKEMVIQ NYVRALTIKY PYWNRTLGAD HFFVSCHGIG NRATAAFPFL 180 LKNAIRLVCS PSYDSNYIPH KDVSLPQILE LSFPPEGDGM WNDSTMESLP IQLSPVETHP 240 SRTKLCFWAG SPNSEVRKNL RVHYKGLEEF EIHFVENVKR ALVLDTFQKE IHRSKFCICP 300 RGKTQVGGVC LAESMAFGCV PVIMSDYYDL PFNDILDWNA FSVILKEHDV PIMGEILKGI 360 PEDMFEKMRQ NVLKVSKYFK WHFRPVKYDE FHMVMYELWK RRHIIRY* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-49 | 61 | 360 | 316 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002266299.1 | 0 | 45 | 407 | 75 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 45 | 407 | 65 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002309859.1 | 0 | 42 | 407 | 63 | 420 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002321656.1 | 0 | 1 | 407 | 1 | 407 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 45 | 407 | 65 | 406 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |