Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.015G124800.2 |
Family | GT47 |
Protein Properties | Length: 417 Molecular Weight: 47307.1 Isoelectric Point: 7.9656 |
Chromosome | Chromosome/Scaffold: 15 Start: 13834878 End: 13838477 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 90 | 402 | 0 |
EKKVRVFMYDLPKKFTTGTIENHALARGSSDLSKVSYPGHQHMGEWYMYLDLSRPDLDRVGSPVVKVNDPEEADLFYVPVFSSLSLIVNPARAGTVPGSD PVYSDEKMQEELVEWLEEQEYWRRNNGRDHVVFAGDPNALYRVLDRVKNAVLLLSDFGRVRSDQGSLIKDVIVPYSHRINVYNGDIGVEERKTLLFFMGN RYRKDGGKIRDLLFQMLEKEEDVVIRHGTQSRENRRTATRGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPLIVSDSIELPFEDVIDYRKIAIFVDTESS LKPGYLVRMLRAV |
Full Sequence |
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Protein Sequence Length: 417 Download |
MSERLKIRTP KSPNSSKLPR IMARKSSLLK QTLIFSACTI LIIYAFFNTF LSSSTAAATT 60 GISATTSSLF AEQISRENLL EFPEKATENE KKVRVFMYDL PKKFTTGTIE NHALARGSSD 120 LSKVSYPGHQ HMGEWYMYLD LSRPDLDRVG SPVVKVNDPE EADLFYVPVF SSLSLIVNPA 180 RAGTVPGSDP VYSDEKMQEE LVEWLEEQEY WRRNNGRDHV VFAGDPNALY RVLDRVKNAV 240 LLLSDFGRVR SDQGSLIKDV IVPYSHRINV YNGDIGVEER KTLLFFMGNR YRKDGGKIRD 300 LLFQMLEKEE DVVIRHGTQS RENRRTATRG MHTSKFCLNP AGDTPSACRL FDSIVSLCVP 360 LIVSDSIELP FEDVIDYRKI AIFVDTESSL KPGYLVRMLR AVSTEKILEY QKQMRE* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-70 | 91 | 402 | 323 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC61825.1 | 0 | 22 | 415 | 1 | 384 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_850241.1 | 0 | 22 | 415 | 1 | 384 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 97 | 416 | 1 | 320 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 22 | 416 | 1 | 395 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 22 | 416 | 1 | 390 | catalytic, putative [Ricinus communis] |