Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.016G011400.1 |
Family | CBM57 |
Protein Properties | Length: 1085 Molecular Weight: 120930 Isoelectric Point: 8.5137 |
Chromosome | Chromosome/Scaffold: 16 Start: 593526 End: 606057 |
Description | Leucine-rich repeat transmembrane protein kinase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
CBM57 | 519 | 679 | 1.7e-25 |
LYINCGGGETVVDGKVFEADSTTSNYNLAPRKNWAYSCSGDFGSKTYDSSDYIKNVECEVCDSAGTQLYNSSRLCPLSLTYYGFCLFKGNYTVKLYFAET VYQSDADYSNLGKRVFDVYIQGKRALKDFNIKEMASGTNKTWTANFTAYVGDDYLLTIDFF |
Full Sequence |
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Protein Sequence Length: 1085 Download |
MHYYLLLNVH FPIRPKKCRH IIKTKQPKLF PATTRINYVS ILVPKINVKR MYCKLLFSGI 60 LIFEQGQFGN GSALQAKVVM AKLHLKLFPK LVSSLAVLLL CQFGYVVCQS TGFSDSRLPA 120 DEEKALDDLL KTLEWGFHPN ISRSACSSNF EYIKCDCNRT VCHVTRLTLP DQDLTGQINA 180 EALASLVHLR AIDLSKNQLH GSIPLTLGNL SSLTRLDLST NFLNGYIPSS LGNLSSLQYL 240 RLSRNFLNDF IPSSLGNLSS LEYLSLSYNK LFGQIPKELG NLSNLLSMYL DFNELTGQLP 300 PELGRLGSLG YLGLSSNNLS GPLPENYANF TGLQWFSVAG NRLTGQVPSF IADWTELNRL 360 SLSGNDFERE LPLESIFNMS NLRYLFVSDV RSSGFPKNAN MKKIRYLMIR NCSISGEIPP 420 YIGDWSRLRY LDLSFNSLTG GIPDSMKKLN LSKMFLTGNM LNGTVPYWVP DTIEDKADLS 480 YNNFEIPRDG PKKGEGKLNM NSIRNLIKKC RRKPKYNSLY INCGGGETVV DGKVFEADST 540 TSNYNLAPRK NWAYSCSGDF GSKTYDSSDY IKNVECEVCD SAGTQLYNSS RLCPLSLTYY 600 GFCLFKGNYT VKLYFAETVY QSDADYSNLG KRVFDVYIQG KRALKDFNIK EMASGTNKTW 660 TANFTAYVGD DYLLTIDFFW AGKGTFQEPS FSYAPAALSL KGPLVSGISV TANFKVGKGL 720 SPSQIAGITV GSVFASVLLS AYMWKMGWQQ QSDLNEVQGD EKSFALKQII DATRKFSPKM 780 EIGRGRFGIV YEAELPNKRK LAVMKISPRN SKQQGKDELQ GEISKLKSLH HENLVQLLRG 840 YSNKDLHLLV NEQKGSLQRA LFEPDSTTKL DWKARFDICL GIARGLTYLH EEKRIVHGNI 900 NPSNIMLDDD SLTAKLSAFG LATLCDEEDP FMTIEAKESR VYMAPEYSMG KTIDTVKADV 960 YSFGVVLLEI VSGTVSAEYT PNQEEAKFLL DKASVLHHKG RILDLVDKKL ASSYDRKQAL 1020 TVLLLAMKCV NLSPTLRPKM SEVVSVLEDE KRIDAISEGD DTPSTNIGGL CGAFSSVLEI 1080 DPIS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN00113 | PLN00113 | 1.0e-22 | 167 | 466 | 304 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
PLN00113 | PLN00113 | 4.0e-31 | 167 | 466 | 305 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
PLN00113 | PLN00113 | 7.0e-36 | 167 | 466 | 303 | + leucine-rich repeat receptor-like protein kinase; Provisional | ||
pfam11721 | Malectin | 3.0e-38 | 518 | 708 | 193 | + Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. | ||
cd00180 | PKc | 2.0e-43 | 782 | 970 | 191 | + Catalytic domain of Protein Kinases. Protein Kinases (PKs), catalytic (c) domain. PKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine or tyrosine residues on protein substrates. The PK family is part of a larger superfamily that includes the catalytic domains of RIO kinases, aminoglycoside phosphotransferase, choline kinase, phosphoinositide 3-kinase (PI3K), and actin-fragmin kinase. PKs make up a large family of serine/threonine kinases, protein tyrosine kinases (PTKs), and dual-specificity PKs that phosphorylate both serine/threonine and tyrosine residues of target proteins. Majority of protein phosphorylation, about 95%, occurs on serine residues while only 1% occurs on tyrosine residues. Protein phosphorylation is a mechanism by which a wide variety of cellular proteins, such as enzymes and membrane channels, are reversibly regulated in response to certain stimuli. PKs often function as components of signal transduction pathways in which one kinase activates a second kinase, which in turn, may act on other kinases; this sequential action transmits a signal from the cell surface to target proteins, which results in cellular responses. The PK family is one of the largest known protein families with more than 100 homologous yeast enzymes and 550 human proteins. A fraction of PK family members are pseudokinases that lack crucial residues for catalytic activity. The mutiplicity of kinases allows for specific regulation according to substrate, tissue distribution, and cellular localization. PKs regulate many cellular processes including proliferation, division, differentiation, motility, survival, metabolism, cell-cycle progression, cytoskeletal rearrangement, immunity, and neuronal functions. Many kinases are implicated in the development of various human diseases including different types of cancer. |
Gene Ontology | |
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GO Term | Description |
GO:0004672 | protein kinase activity |
GO:0005515 | protein binding |
GO:0005524 | ATP binding |
GO:0006468 | protein phosphorylation |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002323147.1 | 0 | 586 | 1056 | 1 | 467 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002323154.1 | 0 | 607 | 1084 | 308 | 787 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002323341.1 | 0.00000004 | 132 | 324 | 43 | 249 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002323341.1 | 0 | 290 | 1051 | 55 | 831 | predicted protein [Populus trichocarpa] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3ulz_A | 3e-36 | 759 | 1048 | 15 | 307 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
PDB | 3uim_A | 3e-36 | 759 | 1048 | 15 | 307 | A Chain A, Structural Basis For The Impact Of Phosphorylation On Plant Receptor- Like Kinase Bak1 Activation |
PDB | 3tl8_H | 9e-36 | 759 | 1048 | 23 | 315 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3tl8_G | 9e-36 | 759 | 1048 | 23 | 315 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
PDB | 3tl8_D | 9e-36 | 759 | 1048 | 23 | 315 | B Chain B, The Avrptob-Bak1 Complex Reveals Two Structurally Similar Kinaseinteracting Domains In A Single Type Iii Effector |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
CV237055 | 283 | 209 | 491 | 0 |
DT472424 | 289 | 75 | 363 | 0 |
CV275474 | 276 | 122 | 397 | 0 |
CV275474 | 214 | 325 | 507 | 0.00002 |
DT472424 | 148 | 325 | 466 | 0.00005 |
Sequence Alignments (This image is cropped. Click for full image.) |
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