y
Basic Information | |
---|---|
Species | Populus trichocarpa |
Cazyme ID | Potri.017G114100.2 |
Family | GT57 |
Protein Properties | Length: 376 Molecular Weight: 42817.9 Isoelectric Point: 8.8173 |
Chromosome | Chromosome/Scaffold: 17 Start: 12938902 End: 12945075 |
Description | ALG6, ALG8 glycosyltransferase family |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT57 | 45 | 374 | 0 |
LLLRVAVSLHSYSGAGTPPKFGDFEAQRHWMEITTNLPIKDWYFNTTNNDLSYWGLDYPPLTAYQSYFHGLFLKHFDPNSVSLFTSRGYETHFGKLLMRW TVLSSDLLIFFPAVLYFVLVYYGGNRSGGNKSDVAWHIAVILINPCLILTDHGHFQYNCISLGLTLGAVAAVLSQKDLLACVLFCLSLNHKQMSAYYAPA FFSHLFGSCLRRKNPPLEVLKLGLTVLGTFAIVWWPFLHSRDAFSVVLSRLAPFERGIYEDYVANFWCCTSVLIKWKRLFTTNSLRFLSLVATILTFLPS MIQQIWSPSSKGFLYGLLNSSLAFYLFSFQ |
Full Sequence |
---|
Protein Sequence Length: 376 Download |
MEKKQRKKVK NPMSETESND LDDISCLFFQ KGIMGLFLLI SIFSLLLRVA VSLHSYSGAG 60 TPPKFGDFEA QRHWMEITTN LPIKDWYFNT TNNDLSYWGL DYPPLTAYQS YFHGLFLKHF 120 DPNSVSLFTS RGYETHFGKL LMRWTVLSSD LLIFFPAVLY FVLVYYGGNR SGGNKSDVAW 180 HIAVILINPC LILTDHGHFQ YNCISLGLTL GAVAAVLSQK DLLACVLFCL SLNHKQMSAY 240 YAPAFFSHLF GSCLRRKNPP LEVLKLGLTV LGTFAIVWWP FLHSRDAFSV VLSRLAPFER 300 GIYEDYVANF WCCTSVLIKW KRLFTTNSLR FLSLVATILT FLPSMIQQIW SPSSKGFLYG 360 LLNSSLAFYL FSFQE* 420 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03155 | Alg6_Alg8 | 1.0e-94 | 48 | 374 | 332 | + ALG6, ALG8 glycosyltransferase family. N-linked (asparagine-linked) glycosylation of proteins is mediated by a highly conserved pathway in eukaryotes, in which a lipid (dolichol phosphate)-linked oligosaccharide is assembled at the endoplasmic reticulum membrane prior to the transfer of the oligosaccharide moiety to the target asparagine residues. This oligosaccharide is composed of Glc(3)Man(9)GlcNAc(2). The addition of the three glucose residues is the final series of steps in the synthesis of the oligosaccharide precursor. Alg6 transfers the first glucose residue, and Alg8 transfers the second one. In the human alg6 gene, a C->T transition, which causes Ala333 to be replaced with Val, has been identified as the cause of a congenital disorder of glycosylation, designated as type Ic OMIM:603147. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0016758 | transferase activity, transferring hexosyl groups |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC79743.1 | 0 | 38 | 374 | 32 | 371 | putative alpha 3 glucosyltransferase [Oryza sativa Japonica Group] |
RefSeq | NP_198662.1 | 0 | 1 | 374 | 1 | 378 | ALG6, ALG8 glycosyltransferase family protein [Arabidopsis thaliana] |
RefSeq | XP_002280181.1 | 0 | 1 | 363 | 1 | 356 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002305159.1 | 0 | 48 | 374 | 15 | 341 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329281.1 | 0 | 38 | 374 | 1 | 337 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
dolichyl-diphosphooligosaccharide biosynthesis | RXN-5470 | EC-2.4.1.267 | Dol-P-Glc:Man9GlcNAc2-PP-Dol α-1,3-glucosyltransferase |