| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.018G025400.1 |
| Family | GT47 |
| Protein Properties | Length: 335 Molecular Weight: 39009.2 Isoelectric Point: 9.4139 |
| Chromosome | Chromosome/Scaffold: 18 Start: 2013627 End: 2014736 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 2 | 285 | 0 |
| EKRFKVHVYSEGELPIVHDGPCKDIYTIEGRFIHEMEHGAKRFKTRDPRRAHVYFMPFSVTWMVKYLYKPLTYDHTAMKQFVADYVRVVSSKYPFWNRTQ GADHFMLSCHDWGPHASHGNPFLYNTSIRVLCNANSSEGFSPRKDVSLPEIHLYGGNVPPKLISPPPATSPRPYLAFFSGGLHGPIRPILLDHWKGRDPD LQVYEYLPKDLDYYSFMLRSKFCLCPSGHEVASPRIVEAIYAECVPVILSDHYVLPFSDVLRWEAFAIQVNVSEIPRLKEVLIS | |||
| Full Sequence |
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| Protein Sequence Length: 335 Download |
| MEKRFKVHVY SEGELPIVHD GPCKDIYTIE GRFIHEMEHG AKRFKTRDPR RAHVYFMPFS 60 VTWMVKYLYK PLTYDHTAMK QFVADYVRVV SSKYPFWNRT QGADHFMLSC HDWGPHASHG 120 NPFLYNTSIR VLCNANSSEG FSPRKDVSLP EIHLYGGNVP PKLISPPPAT SPRPYLAFFS 180 GGLHGPIRPI LLDHWKGRDP DLQVYEYLPK DLDYYSFMLR SKFCLCPSGH EVASPRIVEA 240 IYAECVPVIL SDHYVLPFSD VLRWEAFAIQ VNVSEIPRLK EVLISVPEER YRRLKEGLRA 300 IRKHFVLNQP AKRFDVFHMI LHSIWLRRLN LRLV* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 5.0e-64 | 1 | 286 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI21064.1 | 0 | 1 | 333 | 145 | 477 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197913.4 | 0 | 1 | 334 | 147 | 480 | catalytic [Arabidopsis thaliana] |
| RefSeq | XP_002285237.1 | 0 | 1 | 333 | 1 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002324871.1 | 0 | 1 | 334 | 1 | 334 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002515489.1 | 0 | 1 | 333 | 148 | 480 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DR923559 | 237 | 97 | 333 | 0 |
| GE475605 | 292 | 44 | 333 | 0 |
| FE523338 | 268 | 1 | 267 | 0 |
| GO363500 | 278 | 31 | 307 | 0 |
| DV154957 | 223 | 115 | 332 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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