Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.018G043700.1 |
Family | GT47 |
Protein Properties | Length: 708 Molecular Weight: 78931.4 Isoelectric Point: 7.7238 |
Chromosome | Chromosome/Scaffold: 18 Start: 3790383 End: 3794736 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 376 | 658 | 0 |
ILKVYIYKEGERPILHQAPLKGIYASEGWFMKLLETNKKFVTKDPKKSHLFYLPFSSRNLEVNLYVPNSHSHKNLIQYLKNYLDMISAKYPFWNRTRGAD HFLVACHDWAPTETRQHMANCIRALCNSDAKGGFVFGKDAALPETTVRTPQNLLRDLGGKPASKRSILAFFAGSMHGYLRPILLQHWGNKDPDVKVFGKL PKVKGRGKMNYPQYMKSSKYCICAKGFEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLNWESFAVFVLEKDIPNLKNILLSI |
Full Sequence |
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Protein Sequence Length: 708 Download |
MGQEFRYPCT TEIGKLLWFI GVIVAVVLTF QHFELPYGNI ISSLSSAQKD LGAGNGSLLP 60 HGASSTHEML SNVTQSNGLN YAAGGQETGD NHGTETPANV NNGVVSEGSR GMNESSLVDS 120 RGEESSLDEL VDTNTNSTLY VNNDVGSEGI KGLNKSLGID NHGRESSPEQ LLDQNENSTL 180 ELNHSGNGSA SIETDRSLFR ENITSTSENT GTSQAGITPI APALPPVDSP TNIAIPRNAE 240 PSTLAPVVPV ESNTSKTDKD ASHGLENDGK AGEQLNNSTS LQNNTSVTSV REVKKEPHTP 300 SPAVISISEM NNLQLQSWSS PISRRPRWPS AVDQELLNAK SQIQKAPLVE SDSMLYAPLY 360 RNISMFKKSY ELMEDILKVY IYKEGERPIL HQAPLKGIYA SEGWFMKLLE TNKKFVTKDP 420 KKSHLFYLPF SSRNLEVNLY VPNSHSHKNL IQYLKNYLDM ISAKYPFWNR TRGADHFLVA 480 CHDWAPTETR QHMANCIRAL CNSDAKGGFV FGKDAALPET TVRTPQNLLR DLGGKPASKR 540 SILAFFAGSM HGYLRPILLQ HWGNKDPDVK VFGKLPKVKG RGKMNYPQYM KSSKYCICAK 600 GFEVNSPRVV EAIFYECVPV IISDNFVPPF FEVLNWESFA VFVLEKDIPN LKNILLSIPE 660 NKYREMQMRV KKVQQHFLWH ARPVKYDIFH MILHSVWYNR VFQVHPR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-72 | 377 | 658 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_197954.1 | 0 | 1 | 704 | 1 | 652 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 707 | 1 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 238 | 707 | 2 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 310 | 707 | 1 | 398 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002516499.1 | 0 | 1 | 707 | 1 | 601 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |