Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.018G085400.1 |
Family | GT47 |
Protein Properties | Length: 644 Molecular Weight: 73780.9 Isoelectric Point: 8.991 |
Chromosome | Chromosome/Scaffold: 18 Start: 11219801 End: 11223426 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 312 | 594 | 0 |
RMLKVYVYKEGEKPIFHQSKMRGIYASEGWFMKLIEGNKKFVVRDPRKAHLFYLPFSPHMLRTALFDHNSLNQKELAEFLKNYVDLVAKKYSFWNRTGGT DHFLVGCHDWASQMTRHHMRNCIRVLCNSNVAKGFKIGKDTTLPVTYIRSVENPLKELGGKSPSERPILAFFAGNMHGYLRPILLEYWENKEPDMKILGP MSRDIAGKRRYREYMKRSKYCICARGYEVHTPRVVESIFYECVPVIISDNYVPPLFEVLNWEAFSVFIQEKDIPNLRNILLSI |
Full Sequence |
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Protein Sequence Length: 644 Download |
METSALFQRL CLVEIRRLLM VIGVAIIVII LFQCFALPYG KGWSVSSADE DSVVMLISNP 60 ILSNSSKSSI RVFHIMTNGS DSSDLGEEAR DEDEIENTDA DYELSSNKIE QNDVLLKLGE 120 MLGKSTDNTS SQEKSIETGS KHLKQVGETE ILEATTSSTF GGIQSNVGTV PSVLLGISKK 180 NGENRDRDSI TSDSFFPTKV ISLDHMETQT KNAELLQTIS VTLNNNSTRD SISTLKRWEQ 240 STSISQMNSL LLQSLVYSHS MKPRRLSVRD RELLSAKLEI ENAPRVDNPP GLYASAFRNI 300 SMFKRSYELM ERMLKVYVYK EGEKPIFHQS KMRGIYASEG WFMKLIEGNK KFVVRDPRKA 360 HLFYLPFSPH MLRTALFDHN SLNQKELAEF LKNYVDLVAK KYSFWNRTGG TDHFLVGCHD 420 WASQMTRHHM RNCIRVLCNS NVAKGFKIGK DTTLPVTYIR SVENPLKELG GKSPSERPIL 480 AFFAGNMHGY LRPILLEYWE NKEPDMKILG PMSRDIAGKR RYREYMKRSK YCICARGYEV 540 HTPRVVESIF YECVPVIISD NYVPPLFEVL NWEAFSVFIQ EKDIPNLRNI LLSIPQEKYV 600 AMQLGVKKVQ QHFLWHKKPV KYDLFHMILH SVWHSRVFQM ESK* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-63 | 314 | 594 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 1 | 639 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 1 | 641 | 1 | 711 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 1 | 643 | 1 | 665 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 4 | 643 | 2 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324437.1 | 0 | 310 | 643 | 1 | 334 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |