Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.018G085500.1 |
Family | GT47 |
Protein Properties | Length: 683 Molecular Weight: 78487.9 Isoelectric Point: 9.3272 |
Chromosome | Chromosome/Scaffold: 18 Start: 11225191 End: 11230092 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 350 | 633 | 0 |
ERTLKIYIYKDGKKPIFHLPILKGLYASEGWFMKLMQGNKHFVVKDPRKAHLFYMPFSSRMLEYTLYVRNSHNRTNLRLYMKRYAESIAAKYSFWNRTGG ADHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKIGRDVSFPETYVRSARNPLRDLGGKPPSQRNILAFYAGNMHGYLRPILLKYWKDKDPDMKIFG PMPPGVASKMNYIHHMQRSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFDVLDWGAFSLILAEKDISNLKEILLSI |
Full Sequence |
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Protein Sequence Length: 683 Download |
MELCFQLPKF FQNVNRRWLL VLGVVAVTHT LFQFLLLPYG NALRSLFPNV NDSMYDKSSF 60 AVIQSSKKSV MVRYPLTVDK SSLNNYFKFD GVLENADDSN GGVEEGHDDG TKKNTEDTDH 120 DFSSEEGDME VLDDVIQLEV DRDLEDDFPS EDVKDRHETF ASGGVKTEES NPVLKLANEA 180 RFNLPLERNV KSDHDIPTDN VLQQNKSQAH KEFEHVNSTL PVDSQAVASS TKATYLKSNG 240 SSSIGPAALK SDSAAAKNYS VVLAKPGKKK MRCEMPPKSV TLIDEMNSIL VRHRRSSRSM 300 RPRWSSARDQ EILAARSQIE SAPAVVHDRD LYAPLFRNVS KFKRSYELME RTLKIYIYKD 360 GKKPIFHLPI LKGLYASEGW FMKLMQGNKH FVVKDPRKAH LFYMPFSSRM LEYTLYVRNS 420 HNRTNLRLYM KRYAESIAAK YSFWNRTGGA DHFLVACHDW APYETRHHME HCIKALCNAD 480 VTAGFKIGRD VSFPETYVRS ARNPLRDLGG KPPSQRNILA FYAGNMHGYL RPILLKYWKD 540 KDPDMKIFGP MPPGVASKMN YIHHMQRSKY CICPKGYEVN SPRVVEAIFY ECVPVIISDN 600 FVPPFFDVLD WGAFSLILAE KDISNLKEIL LSIPKEKYLQ MQLGVRKAQR HFLWHASPMK 660 YDLFYMTLHS IWYNRVYQIK PR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-63 | 349 | 633 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 1 | 678 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 1 | 680 | 1 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 271 | 682 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 275 | 682 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 1 | 682 | 1 | 676 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |