y
Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.018G124800.1 |
Family | GT47 |
Protein Properties | Length: 735 Molecular Weight: 84235.9 Isoelectric Point: 9.6334 |
Chromosome | Chromosome/Scaffold: 18 Start: 14786337 End: 14792168 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 400 | 685 | 0 |
KRFKVWPYKEGERPLVHDGPLNNIYSIEGHFIDEVESKGSPFRAQDPDEAHVFFLPVSVASIVHFIYLPITAAADYSRDRLRRVVTDYVHIVAKKYPYWN RSNGADHFMVSCHDWAPDVSIANSELFNKFIRVLCNANISVGFRPPRDVPLPEIYLPFSGLGTTHMGQAPNNRPILAFFEGRAHGYIRQVLFKHWKNKDN EVQVHELLPKGKNYTRLMGQSKFCLCPSGFEVASPRVVEAIYQGCVPVIISNNYSLPFSDVLNWSQFSVQIPVEKIPEIKMILQRI |
Full Sequence |
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Protein Sequence Length: 735 Download |
MSGLRVLKRK GRENMDQTQK KEAAVVLDSC KSSGAIKKMK KDDESQSKGK KTCDLVSFWE 60 LPEYMKDNEF ILSYYRADWP LKKALFSVFR WHNETLNVWT HLLGFFLFVG LTVANLMQGT 120 TELLDLGHNL PMKTDVSSLG MPATRWPFYV FLGGSMFCLL SSSVCHLFSC HSHSLNILLL 180 RMDYVGIVIM IITSFFPPMY YIFQCEPHWQ FIYLGGITVM GMFTIVTLLS PPLSTGKFRA 240 FRAMLFASMG LFGLIPAVHS VIANWSNPKR DTIVAYESAM AIFYLTGTGL YVSRFPERLK 300 PGLFDLTGHS HQIFHVFVVL GALAHYGATL LFLEYRDLVG CEKRSSLERV EEGLSKARAA 360 IQEAIRSKNY TSHKKETFIP KGSVYWNSHA FHQSHIEMVK RFKVWPYKEG ERPLVHDGPL 420 NNIYSIEGHF IDEVESKGSP FRAQDPDEAH VFFLPVSVAS IVHFIYLPIT AAADYSRDRL 480 RRVVTDYVHI VAKKYPYWNR SNGADHFMVS CHDWAPDVSI ANSELFNKFI RVLCNANISV 540 GFRPPRDVPL PEIYLPFSGL GTTHMGQAPN NRPILAFFEG RAHGYIRQVL FKHWKNKDNE 600 VQVHELLPKG KNYTRLMGQS KFCLCPSGFE VASPRVVEAI YQGCVPVIIS NNYSLPFSDV 660 LNWSQFSVQI PVEKIPEIKM ILQRISNSKY LRMHERVKRV QRHFVLNRPA KPFDVIHMVL 720 HSLWLRRLNF RLSD* 780 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01065 | hlyIII | 4.0e-6 | 145 | 333 | 196 | + channel protein, hemolysin III family. This family includes proteins from pathogenic and non-pathogenic bacteria, Homo sapiens and Drosophila. In Bacillus cereus, a pathogen, it has been show to function as a channel-forming cytolysin. The human protein is expressed preferentially in mature macrophages, consistent with a role cytolytic role. | ||
COG1272 | COG1272 | 3.0e-25 | 65 | 336 | 273 | + Predicted membrane protein, hemolysin III homolog [General function prediction only] | ||
pfam03006 | HlyIII | 4.0e-47 | 89 | 326 | 240 | + Haemolysin-III related. Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Saccharomyces cerevisiae protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolism. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adipoQ receptors, and hence have been named PAQR proteins. The mammalian members include progesterone binding proteins. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea. | ||
pfam03016 | Exostosin | 1.0e-64 | 398 | 685 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
GO:0016021 | integral to membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03873.1 | 0 | 345 | 734 | 235 | 615 | Exostosin-like [Medicago truncatula] |
EMBL | CBI25537.1 | 0 | 344 | 732 | 85 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 344 | 732 | 4 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324622.1 | 0 | 1 | 342 | 1 | 342 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324623.1 | 0 | 398 | 734 | 1 | 337 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |