Basic Information | |
---|---|
Species | Populus trichocarpa |
Cazyme ID | Potri.018G124900.1 |
Family | GT47 |
Protein Properties | Length: 467 Molecular Weight: 53304.1 Isoelectric Point: 9.0479 |
Chromosome | Chromosome/Scaffold: 18 Start: 14794888 End: 14797562 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 132 | 416 | 0 |
EKRFKIWVYKEGERPLVHGGPLNNIYGVEGQFLDEMEHGKSPFAASHPDEAHMFLLPISVAYIISYVYKPIVTYSRDELQRLVQDYVGVVADKYPYWNRS KGADHFLVSCHDWAPDISGANPDLYKNFIRVLCNANTSERFEPRRDVSIPEINIPNGKLGPPHKGLPPSKRSIFAFFAGGAHGYIRKVLLENWKDKDDEI QVHEYLDKKGTDYFELMGQSKFCLCPSGYEVASPRVVTAIQLGCVPVTISDNYTLPFSDVLDWSKFSVHIPSEKIPEIKTILKKI |
Full Sequence |
---|
Protein Sequence Length: 467 Download |
METICNGSNV GFMLLPVVVF ASLIVYFGSP LNQNTNTVGY FSSFSTSNTV YTKANELVFE 60 SSQPSPSQPH QLPTQIKRGR EKIEDGLARA RAAILDAARL KNYTSYKEGT YIPKGVIYRN 120 PYAFHQSHTE MEKRFKIWVY KEGERPLVHG GPLNNIYGVE GQFLDEMEHG KSPFAASHPD 180 EAHMFLLPIS VAYIISYVYK PIVTYSRDEL QRLVQDYVGV VADKYPYWNR SKGADHFLVS 240 CHDWAPDISG ANPDLYKNFI RVLCNANTSE RFEPRRDVSI PEINIPNGKL GPPHKGLPPS 300 KRSIFAFFAG GAHGYIRKVL LENWKDKDDE IQVHEYLDKK GTDYFELMGQ SKFCLCPSGY 360 EVASPRVVTA IQLGCVPVTI SDNYTLPFSD VLDWSKFSVH IPSEKIPEIK TILKKISPQR 420 YLMMQMRVIQ VQRHFELNRP ARPYDLLHML LHSVWVRRLN VKVPYR* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-64 | 131 | 416 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_197526.4 | 0 | 73 | 464 | 17 | 408 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 32 | 464 | 34 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002324625.1 | 0 | 131 | 466 | 1 | 336 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331029.1 | 0 | 131 | 465 | 1 | 336 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531945.1 | 0 | 1 | 465 | 1 | 452 | catalytic, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2jhp_A | 0.009 | 250 | 392 | 328 | 457 | A Chain A, The Structure Of Alpha-N-Acetylgalactosaminidase |
PDB | 2jhc_A | 0.009 | 250 | 392 | 328 | 457 | A Chain A, The Structure Of Alpha-N-Acetylgalactosaminidase |
PDB | 2jha_A | 0.009 | 250 | 392 | 328 | 457 | A Chain A, The Structure Of Alpha-N-Acetylgalactosaminidase |
PDB | 2jh9_A | 0.009 | 250 | 392 | 328 | 457 | A Chain A, The Structure Of Alpha-N-Acetylgalactosaminidase |
PDB | 2jh8_A | 0.009 | 250 | 392 | 328 | 457 | A Chain A, The Structure Of Bluetongue Virus Vp4 Reveals A Multifunctional Rna-capping Production-line |
Metabolic Pathways | |||
---|---|---|---|
Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |