Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.018G125000.1 |
Family | GT47 |
Protein Properties | Length: 522 Molecular Weight: 59546.2 Isoelectric Point: 9.5476 |
Chromosome | Chromosome/Scaffold: 18 Start: 14800300 End: 14804865 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 181 | 470 | 0 |
EKRFKVWVYKEGELPVVHGAPVNDIYSIEGQFLDEIESGKSPFIARHPDEAHAFFLPISVAYIIHYVYKPRITFARDQLQRLVTDYVRVVADKYTYWNRT QGADHFSVSCHDWAPDVSRANPELFRYFVRVLCNANISEGFRPQRDVSIPEIFLPVGKLGPPREYTKPPSKRSILAFFAGGAHGHIRKVLLTHWKEKDDE VQVHEYLTQRNKKNTNLYFELMGQSKFCLCPSGHEVASPRVVTAIQLGCVPVTISANYSLPFSDVLDWSKFSVDIPPEKIPEIKTILKGI |
Full Sequence |
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Protein Sequence Length: 522 Download |
MATFNSSAIS FLLLSALVST LFFLCLSPLN QTIRISTPLS SLYSPNYSIE EAKSNHTFER 60 FQSFPSPTTA VGDEEISAPK DKEKISERLP PSPSPSPSPL PLPVHNSSAV SSLPSIPVIT 120 RHEKKKTDFE RIEEGLAQAR AAIYRAIRSQ NSSSYKEGSY IPRGSMYRNQ YAFHQSYTEM 180 EKRFKVWVYK EGELPVVHGA PVNDIYSIEG QFLDEIESGK SPFIARHPDE AHAFFLPISV 240 AYIIHYVYKP RITFARDQLQ RLVTDYVRVV ADKYTYWNRT QGADHFSVSC HDWAPDVSRA 300 NPELFRYFVR VLCNANISEG FRPQRDVSIP EIFLPVGKLG PPREYTKPPS KRSILAFFAG 360 GAHGHIRKVL LTHWKEKDDE VQVHEYLTQR NKKNTNLYFE LMGQSKFCLC PSGHEVASPR 420 VVTAIQLGCV PVTISANYSL PFSDVLDWSK FSVDIPPEKI PEIKTILKGI SSRRYLTMQR 480 RVMQIQRHFM LNRPAQPYDM LHMILHSVWL RRLNVKKDSS I* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 6.0e-57 | 180 | 470 | 308 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_002308053.1 | 0 | 180 | 516 | 1 | 337 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002308055.1 | 0 | 180 | 514 | 1 | 334 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324627.1 | 0 | 180 | 521 | 1 | 342 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002331030.1 | 0 | 180 | 516 | 1 | 337 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531945.1 | 0 | 7 | 516 | 8 | 449 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |