| Basic Information | |
|---|---|
| Species | Populus trichocarpa |
| Cazyme ID | Potri.019G036500.1 |
| Family | GT47 |
| Protein Properties | Length: 473 Molecular Weight: 54480.3 Isoelectric Point: 9.7776 |
| Chromosome | Chromosome/Scaffold: 19 Start: 4131839 End: 4135281 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 139 | 415 | 0 |
| RSFKIYVYPHRRNDPFANVLLPVDFEPGGNYASESYFKKALMKSHFITKDPAKADLFFLPFSITRLRHDPRVGVGGIQDFIRDYILNISRKYPFWNRTGG ADHFYAACHSIGRSAMEKSEEVKFNAIQVVCSSSYFLSGYIAHKDVSLPQIWPRQGDPPNLASSKRKKLAFFAGSINSPVRERLLHSWRNDSEIFAHFGR LTTPYADELLGSKFCLHVKGFEVNTARIGDSLYYGCVPVIIANHYDLPFADILNWKSFSVVVATLDIPLLKKILKGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 473 Download |
| MANTTWLLYY LTRRRFSPSF RSFFFIPTSL ALFTSLFILF YISTTSTLFF SNQQPSIPHL 60 NQPLLSGSSS IPQINISNSA QNPFVHVSNV NRLNENDRDG RESQRSLRPQ FGSSDGIYVN 120 NELFHDKDIF LEDYKQMNRS FKIYVYPHRR NDPFANVLLP VDFEPGGNYA SESYFKKALM 180 KSHFITKDPA KADLFFLPFS ITRLRHDPRV GVGGIQDFIR DYILNISRKY PFWNRTGGAD 240 HFYAACHSIG RSAMEKSEEV KFNAIQVVCS SSYFLSGYIA HKDVSLPQIW PRQGDPPNLA 300 SSKRKKLAFF AGSINSPVRE RLLHSWRNDS EIFAHFGRLT TPYADELLGS KFCLHVKGFE 360 VNTARIGDSL YYGCVPVIIA NHYDLPFADI LNWKSFSVVV ATLDIPLLKK ILKGISSDQY 420 LMFQKKVLEV RKHFQWHCPP VDYDAFYMVM YELWLRRTSV RVSLPVSKNP NH* 480 |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 2.0e-69 | 137 | 415 | 296 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABD28410.1 | 0 | 26 | 464 | 26 | 483 | Exostosin-like [Medicago truncatula] |
| EMBL | CBI39073.1 | 0 | 1 | 466 | 1 | 449 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265438.1 | 0 | 1 | 472 | 1 | 453 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325425.1 | 0 | 137 | 472 | 1 | 332 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002525728.1 | 0 | 137 | 468 | 1 | 332 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
