Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.019G044600.2 |
Family | GT47 |
Protein Properties | Length: 464 Molecular Weight: 53089.2 Isoelectric Point: 9.9793 |
Chromosome | Chromosome/Scaffold: 19 Start: 5293132 End: 5296166 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 71 | 387 | 0 |
QVLKIFMYDLPSEFHFGLLDLKPLGDSVWPDLRAKVPEYPGGLNLQHSIEYWLTLDLLASEVPGIPRAGSAVRVRNSSEADVIFVPFFSSLCYNRYSKVN PHQKKSKDKLLQEKLVKFLTSQKEWKRSGGRDHVLLAHHPNSMLDARVKLWPAIFILADFGRYPPNIANVAKDVIAPYKHVIRSYVNDSSNFDSRPTLLY FQGAIYRKDGGFARQELFYLLKDEKEVHFQFGSVQKDGVGKASQGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPYENVLDYSQFCIFVR TSDAVREKFLVNLIRSI |
Full Sequence |
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Protein Sequence Length: 464 Download |
MAEKHSSSSL GIISRKSMLC LFVFASALFM LSWFFLLRST SSAGFNGLKK PQKKDDLGDV 60 KSSCFDNNHK QVLKIFMYDL PSEFHFGLLD LKPLGDSVWP DLRAKVPEYP GGLNLQHSIE 120 YWLTLDLLAS EVPGIPRAGS AVRVRNSSEA DVIFVPFFSS LCYNRYSKVN PHQKKSKDKL 180 LQEKLVKFLT SQKEWKRSGG RDHVLLAHHP NSMLDARVKL WPAIFILADF GRYPPNIANV 240 AKDVIAPYKH VIRSYVNDSS NFDSRPTLLY FQGAIYRKDG GFARQELFYL LKDEKEVHFQ 300 FGSVQKDGVG KASQGMHSSK FCLNIAGDTP SSNRLFDAIA SHCVPVIISD DIELPYENVL 360 DYSQFCIFVR TSDAVREKFL VNLIRSIKKD EWTRMWKRLK EVENFFEFQY PSREGDAVQM 420 IWQAVARKVP AIRLKVNKLR RFSRFGTQKD GELRKIPSPS NFW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-53 | 73 | 387 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 1 | 463 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
RefSeq | XP_002268382.1 | 0 | 1 | 463 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 1 | 443 | 3 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002325457.1 | 0 | 1 | 463 | 1 | 463 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 49 | 459 | 86 | 496 | catalytic, putative [Ricinus communis] |