y
Basic Information | |
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Species | Populus trichocarpa |
Cazyme ID | Potri.T071700.1 |
Family | GT47 |
Protein Properties | Length: 505 Molecular Weight: 57713.4 Isoelectric Point: 9.2964 |
Chromosome | Chromosome/Scaffold: 76 Start: 155537 End: 168065 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 117 | 427 | 0 |
IRVYVYEMPSKFTYDLLWLFRNTYRNTDNLTSNGSPVHRLIEQHSVDYWLWADLIAPESERLLKSVVRVERQEDADLFYVPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSEGRNHIFPIHHPWSFKSVRRYVKNAIWLLPDMDSTGNWYKPGQVFLEKDLILPYVPNVNLCDTKCISESESKRSTLLYFRGRLK RNAGGKIRAKLVAELSGAEGVFIEEGTAGEGGKAAAQIGMRKSIFCLSPAGDTPSSARLFDAIVSGCIPVVVSDELELPFEGILDYRKIALFVSSSDAVQ PGWLLKFLKGI |
Full Sequence |
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Protein Sequence Length: 505 Download |
MANKQPHILS SRSRSPILLF TICLFAFSLL FLLFSLSTRH PSASPYPNTN PNLSLKPETS 60 FVASLEHFLD HKYPTSSSSS LFPTVSEEDV SRFDDQVFSQ ERDRFYREPY YPLDLPIRVY 120 VYEMPSKFTY DLLWLFRNTY RNTDNLTSNG SPVHRLIEQH SVDYWLWADL IAPESERLLK 180 SVVRVERQED ADLFYVPFFT TISFFLLEKQ QCKALYREAL KWVTDQPAWK RSEGRNHIFP 240 IHHPWSFKSV RRYVKNAIWL LPDMDSTGNW YKPGQVFLEK DLILPYVPNV NLCDTKCISE 300 SESKRSTLLY FRGRLKRNAG GKIRAKLVAE LSGAEGVFIE EGTAGEGGKA AAQIGMRKSI 360 FCLSPAGDTP SSARLFDAIV SGCIPVVVSD ELELPFEGIL DYRKIALFVS SSDAVQPGWL 420 LKFLKGISLA QIRGMQRNLA KYSRHFIYSS PALPLGPEDL VWRMMAGKLV NIRLHTRRSQ 480 RVVKESRSVC ACDCKRANFT VLVL* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-61 | 116 | 427 | 320 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20132.1 | 0 | 124 | 500 | 1 | 377 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197191.1 | 0 | 1 | 496 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 54 | 500 | 59 | 511 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 1 | 504 | 1 | 505 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 42 | 500 | 43 | 502 | catalytic, putative [Ricinus communis] |