Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s100_54V6.1 |
Family | GT13 |
Protein Properties | Length: 448 Molecular Weight: 51772.5 Isoelectric Point: 7.87 |
Chromosome | Chromosome/Scaffold: 100 Start: 279519 End: 282178 |
Description | alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase, putative |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT13 | 26 | 437 | 0 |
LFSVQTKYADRIALAVEGENKCSHSKKALIDQFSVQQGRIVALEDEKERLENKNAQLSLLVRDYRRMGKEVPKLVGTKPVAAVVIMACNRPDYLDRTLNS VLKYQRLVAEKFPLFVSQDGPMESVKAKAKSFVGVGYMQHLEGDPPTRNPGEIVAYYKIARHYKFALSQLFDIRGFEKVIILEDDMEIAPDFFDYFEATS SILDCDKSVVAISSWNDNGQKQFVSDPTALYRSDFFPGLGWMLTREFWDELSPIWPEAYWDDWLRLNSTRKGRQFIRPEICRTYNFGEHGSSMGQFYYKY LVPIKLNDVHVDWKSYDLESMLKEEKFNKELARRIALATPLNNVDENILKMVENVNRDIRIVYNSQMHFESLARAFGVFEEWKDGIPRTSYKGIVVFRWK GNRVFLVRPDSR |
Full Sequence |
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Protein Sequence Length: 448 Download |
MALLECGARV WLLVAAVMFL LLQARLFSVQ TKYADRIALA VEGENKCSHS KKALIDQFSV 60 QQGRIVALED EKERLENKNA QLSLLVRDYR RMGKEVPKLV GTKPVAAVVI MACNRPDYLD 120 RTLNSVLKYQ RLVAEKFPLF VSQDGPMESV KAKAKSFVGV GYMQHLEGDP PTRNPGEIVA 180 YYKIARHYKF ALSQLFDIRG FEKVIILEDD MEIAPDFFDY FEATSSILDC DKSVVAISSW 240 NDNGQKQFVS DPTALYRSDF FPGLGWMLTR EFWDELSPIW PEAYWDDWLR LNSTRKGRQF 300 IRPEICRTYN FGEHGSSMGQ FYYKYLVPIK LNDVHVDWKS YDLESMLKEE KFNKELARRI 360 ALATPLNNVD ENILKMVENV NRDIRIVYNS QMHFESLARA FGVFEEWKDG IPRTSYKGIV 420 VFRWKGNRVF LVRPDSREAL GYNADVF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00761 | Glyco_tranf_GTA_type | 0.006 | 108 | 298 | 191 | + Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities. | ||
pfam03071 | GNT-I | 8.0e-178 | 15 | 441 | 435 | + GNT-I family. Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (GNT-I, GLCNAC-T I) EC:2.4.1.101 transfers N-acetyl-D-glucosamine from UDP to high-mannose glycoprotein N-oligosaccharide. This is an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. The enzyme is an integral membrane protein localised to the Golgi apparatus, and is probably distributed in all tissues. The catalytic domain is located at the C-terminus. | ||
cd02514 | GT13_GLCNAC-TI | 0 | 105 | 436 | 336 | + GT13_GLCNAC-TI is involved in an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (GLCNAC-T I , GNT-I) transfers N-acetyl-D-glucosamine from UDP to high-mannose glycoprotein N-oligosaccharide, an essential step in the synthesis of complex or hybrid-type N-linked oligosaccharides. The enzyme is an integral membrane protein localized to the Golgi apparatus. The catalytic domain is located at the C-terminus. These proteins are members of the glycosy transferase family 13. |
Gene Ontology | |
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GO Term | Description |
GO:0000139 | Golgi membrane |
GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity |
GO:0006487 | protein N-linked glycosylation |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACG37957.1 | 0 | 1 | 441 | 1 | 441 | N-acetylglucosaminyltransferase I [Zea mays] |
EMBL | CAC80700.1 | 0 | 1 | 441 | 1 | 440 | N-acetylglucosaminyltransferase I [Arabidopsis thaliana] |
RefSeq | NP_001142278.1 | 0 | 1 | 441 | 1 | 441 | hypothetical protein LOC100274447 [Zea mays] |
RefSeq | NP_195537.2 | 0 | 1 | 441 | 1 | 440 | CGL1 (COMPLEX GLYCAN LESS 1); alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase/ protein N-acetylglucosaminyltransferase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_001768107.1 | 0 | 1 | 447 | 1 | 449 | predicted protein [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1foa_A | 0 | 105 | 436 | 8 | 339 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 1fo9_A | 0 | 105 | 436 | 8 | 339 | A Chain A, Crystal Structure Of N-acetylglucosaminyltransferase I |
PDB | 1fo8_A | 0 | 105 | 436 | 3 | 334 | A Chain A, Crystal Structure Of N-Acetylglucosaminyltransferase I |
PDB | 2apc_A | 0 | 105 | 436 | 2 | 333 | A Chain A, Crystal Structure Of N-Acetylglucosaminyltransferase I |
PDB | 2am5_A | 0 | 105 | 436 | 2 | 333 | A Chain A, Crystal Structure Of N-Acetylglucosaminyltransferase I |