Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s112_202V6.1 |
Family | GT47 |
Protein Properties | Length: 578 Molecular Weight: 67004.3 Isoelectric Point: 9.381 |
Chromosome | Chromosome/Scaffold: 112 Start: 944765 End: 947284 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 232 | 517 | 0 |
KTFKIYVYRDGFKPLVHGAKTGGIYATEGLFLKRMEDSNNRFTVSEPSKAHMFLLPYSVRQMVDILQDPYSRSMRPLKTFISNYVDTLASKYPYWNRTHG ADHFFVSCHDWAPLSTMLHGELHTNSMKVVCNADLTVNFDIEKDVSIPQTLKGGNQSDLDVGSLGPEERDFLAFYAGQMHGTVRPVLLDYWKGKDPTMKV YEVLPSDIAVNISYAQHMKRSRYCLCPKGFEVNSPRIVEAILSGCVPVIIADNFVLPYNDVLDWTKFSVTVPEEDIPDLKKILSSI |
Full Sequence |
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Protein Sequence Length: 578 Download |
MSSFPNSEWS AQYDEEAAID APIQEHVMQS FSTSSSVGFS YNEQGMLNRG RKGFRGMQQE 60 KNEYRQSFYH LQHRYTKMIT LPVVVIAISV IGLFFALISF RGFFHPTMKA AGAQSGHRGR 120 IFKDLAVAAV DRNSLGDKNQ AQRFLDLEYH TNQTRVGRTG RIFRRRVLDS LQGMLWGTSH 180 PPRNSQLRKA YLRTIRDTRG KEENLYSSED MLHAEVYHNF TYFKERYAEM NKTFKIYVYR 240 DGFKPLVHGA KTGGIYATEG LFLKRMEDSN NRFTVSEPSK AHMFLLPYSV RQMVDILQDP 300 YSRSMRPLKT FISNYVDTLA SKYPYWNRTH GADHFFVSCH DWAPLSTMLH GELHTNSMKV 360 VCNADLTVNF DIEKDVSIPQ TLKGGNQSDL DVGSLGPEER DFLAFYAGQM HGTVRPVLLD 420 YWKGKDPTMK VYEVLPSDIA VNISYAQHMK RSRYCLCPKG FEVNSPRIVE AILSGCVPVI 480 IADNFVLPYN DVLDWTKFSV TVPEEDIPDL KKILSSISNV TYRSMQRRLR YIRRHFLWLE 540 DPEDTQYDSF HMTLYSIWRQ SMNLRRRKPE IFQERMS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-63 | 230 | 517 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABF70140.1 | 0 | 212 | 563 | 179 | 529 | exostosin family protein [Musa balbisiana] |
RefSeq | NP_001041784.1 | 0 | 205 | 563 | 188 | 545 | Os01g0107700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_001769276.1 | 0 | 175 | 577 | 6 | 408 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001781687.1 | 0 | 227 | 563 | 26 | 361 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001783154.1 | 0 | 230 | 573 | 1 | 343 | predicted protein [Physcomitrella patens subsp. patens] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |