Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s117_57V6.1 |
Family | GT64 |
Protein Properties | Length: 770 Molecular Weight: 86960.1 Isoelectric Point: 8.1028 |
Chromosome | Chromosome/Scaffold: 117 Start: 482453 End: 486125 |
Description | glycosyltransferase family protein 47 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT64 | 522 | 759 | 0 |
FTMVAMTYDARLWNLQMYVKHYSRCTSVREIVVVWNKGTPPNPALDFDSAVPVRIRVEPKNSLNNRFKPDHLIKTKAVLELDDDILMTCDDVERGFRAWR EHPNRLVGYYPRLVEGNPLQYRNERYAHSQAGYNMILTGAAFMDNEVAFSKYWSEDAAKGRAVVDELFNCEDILMNFVLANQTSERALEYVHPAWAVDTS KFSSSAISRDTQGHYAKRTECLSRFSEHFNGMPLKRWD |
Full Sequence |
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Protein Sequence Length: 770 Download |
MKATSSPRSV AAVDRCDMKS KCLWPSYGMY TKCHDKLPYR GCGLSTTLLY YIMSFIFFSI 60 VGVFYAWLAF SPYKNISDAV STGCQPDNEG SWSIGLFRGS SPFSLKPIEM TNAPNNETAA 120 WPVANPVFTC ASVTSLTHPS NFVADPFLYI LGSKMYLFFE TKNSLTMQGD IGVAESSDQG 180 LTWKYLGIAL DEEWHLSYPY VFEYEGEIYM MPEGSRNGDL RLYKATKFPV QWEFHKTLID 240 QPLVDASMVQ HDGNYWMFAS NHKRFNSRKN GQLEVWVAPS PLGPWKEHSK NPIRNGPKSD 300 GARNGGSPFV HEGKLYRLGQ DCGETYGRRL RVFHVVTLTK DLYHEVEVPL NLEESKKGRN 360 AWNGMRYHHL NPHQLPSGEW IAVGDGDRVP SGDLEMQLAL GVGALLIVVL LSITVGVVSG 420 YGRCWLPPLS ITLPGSKKPT ETLLPWVMRP QLSGRLYRSV SRLNRVGSTL RKSLPANSCF 480 RCSFGVLCFV ISVCAICVVV SSFFGGNGAQ EPHPVNGQYS QFTMVAMTYD ARLWNLQMYV 540 KHYSRCTSVR EIVVVWNKGT PPNPALDFDS AVPVRIRVEP KNSLNNRFKP DHLIKTKAVL 600 ELDDDILMTC DDVERGFRAW REHPNRLVGY YPRLVEGNPL QYRNERYAHS QAGYNMILTG 660 AAFMDNEVAF SKYWSEDAAK GRAVVDELFN CEDILMNFVL ANQTSERALE YVHPAWAVDT 720 SKFSSSAISR DTQGHYAKRT ECLSRFSEHF NGMPLKRWDF LSRQDGWDN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd08991 | GH43_bXyl_2 | 0.006 | 133 | 299 | 170 | + Glycosyl hydrolase family 43. This glycosyl hydrolase family 43 (GH43) includes enzymes that have been characterized with xylan-digesting beta-xylosidase (EC 3.2.1.37) and xylanase (endo-alpha-L-arabinanase) activities. These are all inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
cd08991 | GH43_bXyl_2 | 0.002 | 199 | 316 | 129 | + Glycosyl hydrolase family 43. This glycosyl hydrolase family 43 (GH43) includes enzymes that have been characterized with xylan-digesting beta-xylosidase (EC 3.2.1.37) and xylanase (endo-alpha-L-arabinanase) activities. These are all inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
cd08999 | GH43_ABN_2 | 0.001 | 229 | 301 | 74 | + Glycosyl hydrolase family 43. This glycosyl hydrolase family 43 (GH43) includes mostly enzymes with alpha-L-arabinofuranosidase (AFN; EC 3.2.1.55) and endo-alpha-L-arabinanase (ABN; EC 3.2.1.99) activities. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. The GH43 ABN enzymes hydrolyze alpha-1,5-L-arabinofuranoside linkages while the ABF enzymes cleave arabinose side chains so that the combined actions of these two enzymes reduce arabinan to L-arabinose and/or arabinooligosaccharides. These arabinan-degrading enzymes are important in the food industry for efficient production of L-arabinose from agricultural waste; L-arabinose is often used as a bioactive sweetener. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
cd08984 | GH43_5 | 0.0001 | 170 | 298 | 150 | + Glycosyl hydrolase family 43. This glycosyl hydrolase family 43 (GH43) includes enzymes with beta-1,4-xylosidase (xylan 1,4-beta-xylosidase; EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanase and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
pfam09258 | Glyco_transf_64 | 7.0e-70 | 522 | 767 | 247 | + Glycosyl transferase family 64 domain. Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate. |
Gene Ontology | |
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GO Term | Description |
GO:0016758 | transferase activity, transferring hexosyl groups |
GO:0031227 | intrinsic to endoplasmic reticulum membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001765032.1 | 0 | 33 | 769 | 2 | 738 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001769705.1 | 0 | 29 | 769 | 1 | 741 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001778644.1 | 0 | 18 | 769 | 1 | 751 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002262646.1 | 0 | 78 | 768 | 67 | 755 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002532924.1 | 0 | 81 | 768 | 18 | 703 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1on8_B | 2e-25 | 514 | 767 | 22 | 284 | A Chain A, Crystal Structure Of Amylomaltase From Thermus Aquaticus, A Glycosyltransferase Catalysing The Production Of Large Cyclic Glucans |
PDB | 1on8_A | 2e-25 | 514 | 767 | 22 | 284 | A Chain A, Crystal Structure Of Amylomaltase From Thermus Aquaticus, A Glycosyltransferase Catalysing The Production Of Large Cyclic Glucans |
PDB | 1on6_B | 2e-25 | 514 | 767 | 22 | 284 | A Chain A, Crystal Structure Of Amylomaltase From Thermus Aquaticus, A Glycosyltransferase Catalysing The Production Of Large Cyclic Glucans |
PDB | 1on6_A | 2e-25 | 514 | 767 | 22 | 284 | A Chain A, Crystal Structure Of Amylomaltase From Thermus Aquaticus, A Glycosyltransferase Catalysing The Production Of Large Cyclic Glucans |
PDB | 1omz_B | 2e-25 | 514 | 767 | 22 | 284 | A Chain A, Crystal Structure Of Amylomaltase From Thermus Aquaticus, A Glycosyltransferase Catalysing The Production Of Large Cyclic Glucans |