| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s131_65V6.1 |
| Family | GT1 |
| Protein Properties | Length: 615 Molecular Weight: 68067.8 Isoelectric Point: 5.9369 |
| Chromosome | Chromosome/Scaffold: 131 Start: 249448 End: 252942 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT1 | 75 | 583 | 2.1e-31 |
| TRLARSGVAFVGVSAPPVLPGRTAASSEAEIGHSSGASEDDDRQLREALEMELREECLTAMDSVMGAADDAEGNAVIFNFFALEGWHLAELYRVPCTVLA PYVVPYSAPSSFERRFRAAHPLLYRLQEAAPGEVGWKEVMHWMWPLFTDRWAEWRLHRLHLSACPLTDPVTDLPLVYEWPQAPHLLYGFSSQVVECPAYW PSSISVCGFWFTPLEWDVAPEVNPGLSVVQAKPKSLKGPASFRGAPLDLVVRQSCLVTETLQHGKQSIQAVKKTTLSTHNFQLECNPEENPQLEIFAGST KKRSYKPPVKLGHFLSEHKFDESENKDDRPIFLGFSSTGNMGFLERPGSMLKVLKAVLEATDSSAILFTAGHPPLDLEVTELCDENLSTQYLEAEQKRNL LQEGLCCFNGRLFCYSGSVPYLWLLPHCSVAIHHGGSGTTAACLRAGTPQIICPFVLDQFYWAERMTWLRVAPQSLTPQLLMPDMSSSENFHDAVKVISA AIREARSVE | |||
| Full Sequence |
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| Protein Sequence Length: 615 Download |
| MCDAPQLGWL QSKTGKTPES WRQEAEMKKR RVAVFSFGTR GDVLPVAVVA DSLARADRSA 60 SITFITHEAH RDLETRLARS GVAFVGVSAP PVLPGRTAAS SEAEIGHSSG ASEDDDRQLR 120 EALEMELREE CLTAMDSVMG AADDAEGNAV IFNFFALEGW HLAELYRVPC TVLAPYVVPY 180 SAPSSFERRF RAAHPLLYRL QEAAPGEVGW KEVMHWMWPL FTDRWAEWRL HRLHLSACPL 240 TDPVTDLPLV YEWPQAPHLL YGFSSQVVEC PAYWPSSISV CGFWFTPLEW DVAPEVNPGL 300 SVVQAKPKSL KGPASFRGAP LDLVVRQSCL VTETLQHGKQ SIQAVKKTTL STHNFQLECN 360 PEENPQLEIF AGSTKKRSYK PPVKLGHFLS EHKFDESENK DDRPIFLGFS STGNMGFLER 420 PGSMLKVLKA VLEATDSSAI LFTAGHPPLD LEVTELCDEN LSTQYLEAEQ KRNLLQEGLC 480 CFNGRLFCYS GSVPYLWLLP HCSVAIHHGG SGTTAACLRA GTPQIICPFV LDQFYWAERM 540 TWLRVAPQSL TPQLLMPDMS SSENFHDAVK VISAAIREAR SVEMKLCASS LSVKLEGEDG 600 TSVAVSILRT LLCK* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 2.0e-6 | 492 | 579 | 95 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| cd03784 | GT1_Gtf_like | 9.0e-14 | 31 | 285 | 255 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| COG1819 | COG1819 | 1.0e-16 | 491 | 583 | 100 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 2.0e-23 | 401 | 611 | 211 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABR16515.1 | 0 | 23 | 298 | 4 | 275 | unknown [Picea sitchensis] |
| RefSeq | XP_001770940.1 | 0 | 27 | 303 | 1 | 278 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001770940.1 | 0 | 355 | 614 | 263 | 507 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002528612.1 | 0 | 24 | 293 | 2 | 267 | conserved hypothetical protein [Ricinus communis] |
| RefSeq | XP_002528612.1 | 0 | 383 | 609 | 294 | 505 | conserved hypothetical protein [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1iir_A | 0.00000005 | 439 | 608 | 231 | 394 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 3h4t_A | 0.00000009 | 460 | 608 | 239 | 377 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 3h4i_A | 0.00000009 | 460 | 608 | 239 | 377 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 3oth_B | 0.00002 | 493 | 534 | 300 | 341 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 3oth_A | 0.00002 | 493 | 534 | 300 | 341 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| BJ586500 | 234 | 382 | 615 | 0 |
| BJ587949 | 218 | 398 | 615 | 0 |
| BJ595021 | 209 | 407 | 615 | 0 |
| BY970650 | 189 | 62 | 250 | 0 |
| BJ605106 | 161 | 455 | 615 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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