| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s13_216V6.1 |
| Family | GT47 |
| Protein Properties | Length: 490 Molecular Weight: 56050.4 Isoelectric Point: 8.9201 |
| Chromosome | Chromosome/Scaffold: 13 Start: 1424699 End: 1428568 |
| Description | FRA8 homolog |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 139 | 437 | 0 |
| NGIRIYVYDLPAKFNEDWLADERCSNHLFAAEVAIHKVLMTSPIRTLDPCEADFFFIPVYVSCKFTPKTGFPWLGQARKFMEAAVNHVSTRMEFWNRSGG RDHIFVASHDYGACFHTLETEAIAHGIPEFMRKSLILQTFGVQDFHPCQAAEHIQIPPYVSPSVAASYIKDPPERQKRNIFAFFRGKMEINPKNVSGLVY SRGVRTVLYKKFSHNRRFLLKRHRTDNYQLEMLRSTFCLCPVGWAPWSPRIVEAVVHGCVPVIIADNISLPYSHAIDWTGISLSVREHDVPKLDKILLN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 490 Download |
| MHRVSVVLKS NGHREIPSYS SFTSFSKNKH EAPVASHSYW EKPRYLVLGI CILFSVFALC 60 FFILPASMEF TVGNSEPGHQ GLLRKNLRGL QTEETTNALS EEIGEESKNK EWRLKPDHFT 120 LFNTSSLLTT PFNPLNLTNG IRIYVYDLPA KFNEDWLADE RCSNHLFAAE VAIHKVLMTS 180 PIRTLDPCEA DFFFIPVYVS CKFTPKTGFP WLGQARKFME AAVNHVSTRM EFWNRSGGRD 240 HIFVASHDYG ACFHTLETEA IAHGIPEFMR KSLILQTFGV QDFHPCQAAE HIQIPPYVSP 300 SVAASYIKDP PERQKRNIFA FFRGKMEINP KNVSGLVYSR GVRTVLYKKF SHNRRFLLKR 360 HRTDNYQLEM LRSTFCLCPV GWAPWSPRIV EAVVHGCVPV IIADNISLPY SHAIDWTGIS 420 LSVREHDVPK LDKILLNVAA TNLSTIQHNL WKEENRRALL FTDPLVKGDA TWHVFDRLST 480 KLERSFIKH* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 1.0e-69 | 140 | 435 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33322.1 | 0 | 136 | 486 | 83 | 434 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | XP_001754437.1 | 0 | 137 | 489 | 1 | 353 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001777222.1 | 0 | 125 | 486 | 4 | 365 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001781950.1 | 0 | 137 | 489 | 1 | 353 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002275679.1 | 0 | 120 | 483 | 76 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
