| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s140_141V6.1 |
| Family | GH31 |
| Protein Properties | Length: 988 Molecular Weight: 110307 Isoelectric Point: 5.2559 |
| Chromosome | Chromosome/Scaffold: 140 Start: 827865 End: 835789 |
| Description | heteroglycan glucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH31 | 161 | 572 | 0 |
| PTPEVLMTSLSHAIGTMQMPPKWALGYQQCRWSYETAARVSEVATTFRAKKIPCDVMWMDIDYMQGFRCFTFDKDAFPDPKGLSDELHSIGFKGIWMLDP GIMAEEGYEAYDSGCEADVWIQTADGKPYVGECWPGPVVFPDFLNKKTREWWAGLVKKFVAIGVDGIWNDMNEPAVFKTVSKTMPETNIHLGDEEVGGRQ SHSHYHNVYGMFQARSTYEGMLLANENKRPFVLTRAAFIGAHRYAATWTGDNLANWEHLGMSIPMALNLGLSGQPFSGPDIGGFAGDSTPKMFARWMGLG AMLPFARGHSEQGTIDQEPWSFGPEVEELSRIALNRRYRLLHHFYTLFHKAHVTGVPVMTPVFFADPTDPKLRKIDDSFLLGSILVKTWPSPKKRDCNAA FLLPKGIWQRFH | |||
| Full Sequence |
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| Protein Sequence Length: 988 Download |
| MATHLPIVEK SVYRFDESES ARNEAAPSVS FLNPKLREEE IKVPDNEPVI FPEFERDGIY 60 QVVTLKFSPG TSFYGTGEVG GPVERTGKRI YSWNTDAWGY NQNTTSLYQS HPWVFVVLPT 120 GEAFGVLADT TRRCEIDLRK DAIIKIVAVA PFPVVTFGPF PTPEVLMTSL SHAIGTMQMP 180 PKWALGYQQC RWSYETAARV SEVATTFRAK KIPCDVMWMD IDYMQGFRCF TFDKDAFPDP 240 KGLSDELHSI GFKGIWMLDP GIMAEEGYEA YDSGCEADVW IQTADGKPYV GECWPGPVVF 300 PDFLNKKTRE WWAGLVKKFV AIGVDGIWND MNEPAVFKTV SKTMPETNIH LGDEEVGGRQ 360 SHSHYHNVYG MFQARSTYEG MLLANENKRP FVLTRAAFIG AHRYAATWTG DNLANWEHLG 420 MSIPMALNLG LSGQPFSGPD IGGFAGDSTP KMFARWMGLG AMLPFARGHS EQGTIDQEPW 480 SFGPEVEELS RIALNRRYRL LHHFYTLFHK AHVTGVPVMT PVFFADPTDP KLRKIDDSFL 540 LGSILVKTWP SPKKRDCNAA FLLPKGIWQR FHFDDDHPEL PLLFLKGGAI VPTGPVIQCT 600 AEASPTDTIT LLIALDYNGK AAGSLYEDGG DGFDFKNGDY LVTHYEAERV PSLKSKDGEV 660 VIRVASTEGH RERPKRTLHV RLLIGENVEV EGECVDGEEL RIHLPTEDEI NKSVIVKRET 720 GFSKLERMQS LLDEVFEDHH PIMGVGAVKM PEDLDKGNVF VKVVPWLGGH IMSMIHKPSG 780 YDWMEGRLEN GGYEEFSGTE FKSAGWNEDY KVVKRDVAQI SGYEVLGMEG DIGGGLILAR 840 EILLPHDSLS KVKISSSIVA RSVGAGSGGF SRLVRLRIHP MFKIVHPMAS YIKYKAIDGT 900 ARELKPNMEF GEFPIEGSDR PNGEWMLLDS ETGLAIVNTF DIKEVESCHV KWGPGSVTLE 960 LWSAERPVSK ETPLSISHEY DLIDTSE* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1501 | COG1501 | 5.0e-134 | 39 | 627 | 610 | + Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism] | ||
| cd06603 | GH31_GANC_GANAB_alpha | 4.0e-136 | 175 | 515 | 345 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. | ||
| pfam01055 | Glyco_hydro_31 | 9.0e-171 | 171 | 591 | 441 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
| PLN02763 | PLN02763 | 0 | 1 | 985 | 985 | + hydrolase, hydrolyzing O-glycosyl compounds | ||
| cd06604 | GH31_glucosidase_II_MalA | 0 | 175 | 515 | 342 | + Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This family also includes the MalA alpha-glucosidase from Sulfolobus sulfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001752711.1 | 0 | 5 | 987 | 6 | 966 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001760285.1 | 0 | 5 | 983 | 10 | 1024 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001763366.1 | 0 | 5 | 985 | 11 | 975 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001771658.1 | 0 | 1 | 987 | 1 | 965 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001778632.1 | 0 | 65 | 986 | 1 | 914 | predicted protein [Physcomitrella patens subsp. patens] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3w38_A | 0 | 43 | 663 | 179 | 833 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
| PDB | 3w37_A | 0 | 43 | 663 | 179 | 833 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
| PDB | 2g3n_F | 0 | 75 | 592 | 66 | 609 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
| PDB | 2g3n_E | 0 | 75 | 592 | 66 | 609 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
| PDB | 2g3n_D | 0 | 75 | 592 | 66 | 609 | A Chain A, Glu381ser Mutant Of Maize Cytokinin OxidaseDEHYDROGENASE COMPLEXED With N6-Isopentenyladenosine |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| starch degradation I | RXN-2141 | EC-3.2.1.20 | α-glucosidase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HO779383 | 657 | 330 | 982 | 0 |
| HO783906 | 313 | 212 | 524 | 0 |
| JG635864 | 268 | 187 | 454 | 0 |
| ES901722 | 269 | 258 | 526 | 0 |
| HO783906 | 80 | 458 | 534 | 0.004 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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