| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s159_62V6.1 |
| Family | GT1 |
| Protein Properties | Length: 629 Molecular Weight: 69400.9 Isoelectric Point: 8.8636 |
| Chromosome | Chromosome/Scaffold: 159 Start: 352651 End: 359038 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 173 | 582 | 0 |
| IVGTRGDVQPFIAIGKKLQEYGHQVRLATHANFRDFVKKEGLEFYPLGGDPKVLAEYMVKNKGFLPSGPSEISVQRKQIKSIVYSLLDACIKPDKDTGVH FRPHAIIANPPAYGHVHVAEYLKVPLHIFFTMPWTATSAFPHPLSRVKQSAGNRLSYQVVDSLIWLGIRGIINSFRKKHLKLRPITYLSGSQGSISDLPT GYIWSPHLVPKPSDWGPLVDVVGFCFLNLAQNYKPPDDLVKWLNAGSAPIYIGFGSLPVEDPEGMTKIIVEALNKTGQRGIIGRGWGGIGKLDKTPDNVY LLSDCPHDWLFPRCAAVVHHGGAGTTAAGLKAACPTTIVPFFGDQPFWGERVHEKGVGPAPIPVKHFDLEKLVSAIEFMLDRSVKKAALDLAKGMEGEDG IQGAVNAFHK | |||
| Full Sequence |
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| Protein Sequence Length: 629 Download |
| MPSTVASTDA PEKILEEIAD VKTPPLTPQV TEESNHSSLS GTPVKDQMAR ATSMPVADYK 60 MPDQLLQGHL AHSSTLKRRI KKNLDNANVR VAEAKLSDRK KKRLMRQFVS IQTDGGVEFD 120 LGRSSGLARD LFGEHVMDEE KFDHKIPAAD QIEEGDEEND QNPIPPLKIV MLIVGTRGDV 180 QPFIAIGKKL QEYGHQVRLA THANFRDFVK KEGLEFYPLG GDPKVLAEYM VKNKGFLPSG 240 PSEISVQRKQ IKSIVYSLLD ACIKPDKDTG VHFRPHAIIA NPPAYGHVHV AEYLKVPLHI 300 FFTMPWTATS AFPHPLSRVK QSAGNRLSYQ VVDSLIWLGI RGIINSFRKK HLKLRPITYL 360 SGSQGSISDL PTGYIWSPHL VPKPSDWGPL VDVVGFCFLN LAQNYKPPDD LVKWLNAGSA 420 PIYIGFGSLP VEDPEGMTKI IVEALNKTGQ RGIIGRGWGG IGKLDKTPDN VYLLSDCPHD 480 WLFPRCAAVV HHGGAGTTAA GLKAACPTTI VPFFGDQPFW GERVHEKGVG PAPIPVKHFD 540 LEKLVSAIEF MLDRSVKKAA LDLAKGMEGE DGIQGAVNAF HKHIHKGLPD ILKEPPLEEL 600 HHQRHHGILF RIKRKCKSMI HHSSSDPA* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 2.0e-32 | 168 | 582 | 429 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 5.0e-33 | 169 | 313 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 1.0e-114 | 168 | 583 | 420 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001769124.1 | 0 | 103 | 626 | 1 | 522 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001773142.1 | 0 | 137 | 628 | 1 | 492 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001778784.1 | 0 | 95 | 592 | 12 | 512 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001780556.1 | 0 | 103 | 620 | 1 | 516 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002301763.1 | 0 | 71 | 584 | 5 | 509 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 6e-30 | 167 | 586 | 1 | 383 | X Chain X, Crystal Structure Of The Full-Length Autotransporter Esta From Pseudomonas Aeruginosa |
| PDB | 3h4i_A | 6e-30 | 167 | 586 | 1 | 383 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 3e-22 | 167 | 572 | 1 | 387 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 3e-22 | 167 | 572 | 1 | 387 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1iir_A | 5e-20 | 410 | 535 | 229 | 354 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FC354841 | 261 | 136 | 396 | 0 |
| FC430776 | 240 | 190 | 429 | 0 |
| GT046352 | 335 | 176 | 510 | 0 |
| HO626576 | 428 | 165 | 588 | 0 |
| GT046352 | 32 | 503 | 534 | 0.002 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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