Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s15_171V6.1 |
Family | GH19 |
Protein Properties | Length: 299 Molecular Weight: 32331.6 Isoelectric Point: 7.651 |
Chromosome | Chromosome/Scaffold: 15 Start: 1109980 End: 1111283 |
Description | homolog of carrot EP3-3 chitinase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH19 | 86 | 286 | 0 |
SFFPSSLFDKWFPNCNSFYTYEAFIAAAALYPAFGSSRNPEIQKREVAAFFAHVNHETEGLVYIEEINKSFSYCRERDSYGCAPGKKYYSRGPLQLSWNY NYKLASSKVGFNIWADPDKIATDVTLAFKTALWFWMEPATPKPSCHSVIVGDQGFGTTTNIINGGLECGPNNSPAQAENRSKYYQDFCRQLNVSPGGALT C |
Full Sequence |
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Protein Sequence Length: 299 Download |
MFVKIKTLSM TSCRVALLLL VVCFSGLAKA EDCGWQANGA RCSPSTVCCS QWGYCGVTPE 60 HCGTGCQSGS CTGGSPPSPG GSGLSSFFPS SLFDKWFPNC NSFYTYEAFI AAAALYPAFG 120 SSRNPEIQKR EVAAFFAHVN HETEGLVYIE EINKSFSYCR ERDSYGCAPG KKYYSRGPLQ 180 LSWNYNYKLA SSKVGFNIWA DPDKIATDVT LAFKTALWFW MEPATPKPSC HSVIVGDQGF 240 GTTTNIINGG LECGPNNSPA QAENRSKYYQ DFCRQLNVSP GGALTCSNMT PYGLLVGL* 300 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00035 | ChtBD1 | 8.0e-7 | 33 | 62 | 30 | + Hevein or type 1 chitin binding domain. Hevein or type 1 chitin binding domain (ChtBD1), a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins such as hevein, a major IgE-binding allergen in natural rubber latex, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements. | ||
cd06921 | ChtBD1_GH19_hevein | 6.0e-7 | 31 | 62 | 32 | + Hevein or Type 1 chitin binding domain subfamily co-occuring with family 19 glycosyl hydrolases or with barwin domains. This subfamily includes Hevein, a major IgE-binding allergen in natural rubber latex. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements. | ||
cd00442 | lysozyme_like | 1.0e-10 | 133 | 229 | 97 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
pfam00182 | Glyco_hydro_19 | 2.0e-57 | 128 | 286 | 185 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 2.0e-61 | 120 | 286 | 193 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. |
Gene Ontology | |
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GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0008061 | chitin binding |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAT40013.1 | 0 | 10 | 292 | 2 | 319 | chitinase [Zea mays subsp. parviglumis] |
GenBank | AAT40027.1 | 0 | 10 | 292 | 2 | 319 | chitinase [Zea diploperennis] |
GenBank | ACJ62086.1 | 0 | 10 | 292 | 1 | 318 | chitinase [Zea mays subsp. parviglumis] |
GenBank | ACJ62105.1 | 0 | 15 | 292 | 3 | 315 | chitinase [Zea mays subsp. parviglumis] |
RefSeq | XP_001754906.1 | 0 | 10 | 298 | 1 | 289 | predicted protein [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3iwr_B | 0 | 31 | 298 | 2 | 306 | B Chain B, Reassembly And Co-Crystallization Of A Family 9 Processive Endoglucanase From Separately Expressed Gh9 And Cbm3c Modules |
PDB | 3iwr_A | 0 | 31 | 298 | 2 | 306 | B Chain B, Reassembly And Co-Crystallization Of A Family 9 Processive Endoglucanase From Separately Expressed Gh9 And Cbm3c Modules |
PDB | 2dkv_A | 0 | 31 | 298 | 2 | 306 | A Chain A, Crystal Structure Of Class I Chitinase From Oryza Sativa L. Japonica |
PDB | 3cql_B | 0 | 83 | 293 | 1 | 243 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 3cql_A | 0 | 83 | 293 | 1 | 243 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |