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Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s180_124V6.1 |
Family | GT35 |
Protein Properties | Length: 830 Molecular Weight: 93739 Isoelectric Point: 6.8263 |
Chromosome | Chromosome/Scaffold: 180 Start: 774920 End: 781286 |
Description | alpha-glucan phosphorylase 2 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT35 | 103 | 818 | 0 |
ALKALGYHLEETVEEERDAGLGNGGLGRLASCFLDSMATLSIPSVGYGIRYKYGIFEQLIQDNKQIERPDYWLSKGNPWEIERLDVVYPVRFYGHVVTHH QDGKTLFKWEGGEVVQAVAYDTPIPGFGTVNTNTMRLWSARPLEEFGLGEFNEGHYAQAVEARVRAEAISSVLYPNDNHDAGKELRLKQQYFFVSATLQD IMKRYKASGDAISKFDTKVAVQLNDTHPTIAIPELMRLFLDEEGMSWDAAWDITTRVFGYTNHTILPEALEKWSVPLMQKLLPRHLEIIYEINHRHLQVV EGKWKNDTEKLIKMSIIEEGNTKAVRMAILATVGSHAINGVAEIHSGLVKTSLFPEFVELSPQKFQNKTNGVTPRRWILQANPGLSKIITKAVETEDWVL NLDLLQRMKHLAGNKTLQHDFQAAKSANKAKLAALIKSRCGVEVSEKALFDVQIKRIHEYKRQLLNILSLIYRYQCIKRASPADRAKFVKRVAIFAGKAA PGYYLAKRIIQLINAVGARVNNDPDVGDTLKVVFIPNYSVSLAEVIIPANDISQHISTAGMEASGTSNMKFVMNGGLIVGTMDGANIEIANACGRENMFV FGATAEEVGGLRHALKHKGEDLIDERLLQVYHSIEAGDFGPYEEFEPILYSLREGRDYYLLAHDWPSYLDAQEMVDQIFVDESEWTRRCITSTSMMGVFS SDRTIAEYAKDIWNVK |
Full Sequence |
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Protein Sequence Length: 830 Download |
MHLFGNGSTK QAPEEVEHLQ RELLHHAQVT YAHPRPSFNT SVMYEATAQT VRDRLVERWL 60 KTEEHYTKTN AKRIYYLSLE YLVGRSLLNA ILNLRLKGEY SEALKALGYH LEETVEEERD 120 AGLGNGGLGR LASCFLDSMA TLSIPSVGYG IRYKYGIFEQ LIQDNKQIER PDYWLSKGNP 180 WEIERLDVVY PVRFYGHVVT HHQDGKTLFK WEGGEVVQAV AYDTPIPGFG TVNTNTMRLW 240 SARPLEEFGL GEFNEGHYAQ AVEARVRAEA ISSVLYPNDN HDAGKELRLK QQYFFVSATL 300 QDIMKRYKAS GDAISKFDTK VAVQLNDTHP TIAIPELMRL FLDEEGMSWD AAWDITTRVF 360 GYTNHTILPE ALEKWSVPLM QKLLPRHLEI IYEINHRHLQ VVEGKWKNDT EKLIKMSIIE 420 EGNTKAVRMA ILATVGSHAI NGVAEIHSGL VKTSLFPEFV ELSPQKFQNK TNGVTPRRWI 480 LQANPGLSKI ITKAVETEDW VLNLDLLQRM KHLAGNKTLQ HDFQAAKSAN KAKLAALIKS 540 RCGVEVSEKA LFDVQIKRIH EYKRQLLNIL SLIYRYQCIK RASPADRAKF VKRVAIFAGK 600 AAPGYYLAKR IIQLINAVGA RVNNDPDVGD TLKVVFIPNY SVSLAEVIIP ANDISQHIST 660 AGMEASGTSN MKFVMNGGLI VGTMDGANIE IANACGRENM FVFGATAEEV GGLRHALKHK 720 GEDLIDERLL QVYHSIEAGD FGPYEEFEPI LYSLREGRDY YLLAHDWPSY LDAQEMVDQI 780 FVDESEWTRR CITSTSMMGV FSSDRTIAEY AKDIWNVKSA PVPSDAKHQ* 840 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd04300 | GT1_Glycogen_Phosphorylase | 0 | 20 | 817 | 805 | + This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
TIGR02093 | P_ylase | 0 | 24 | 817 | 797 | + glycogen/starch/alpha-glucan phosphorylases. This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources [Energy metabolism, Biosynthesis and degradation of polysaccharides]. | ||
pfam00343 | Phosphorylase | 0 | 103 | 818 | 719 | + Carbohydrate phosphorylase. The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin. | ||
PRK14986 | PRK14986 | 0 | 46 | 818 | 777 | + glycogen phosphorylase; Provisional | ||
COG0058 | GlgP | 0 | 44 | 818 | 782 | + Glucan phosphorylase [Carbohydrate transport and metabolism] |
Gene Ontology | |
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GO Term | Description |
GO:0004645 | phosphorylase activity |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAS88897.1 | 0 | 8 | 829 | 43 | 869 | PHOII [Ostreococcus tauri] |
GenBank | EEH54065.1 | 0 | 8 | 821 | 88 | 904 | glycosyltransferase family 35 protein [Micromonas pusilla CCMP1545] |
GenBank | EFA85934.1 | 0 | 17 | 824 | 41 | 846 | glycogen phosphorylase 1 [Polysphondylium pallidum PN500] |
RefSeq | XP_001774678.1 | 0 | 1 | 823 | 1 | 851 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002509323.1 | 0 | 15 | 829 | 44 | 859 | glycosyltransferase family 35 protein [Micromonas sp. RCC299] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ygp_B | 0 | 15 | 818 | 40 | 876 | A Chain A, Phosphorylated Form Of Yeast Glycogen Phosphorylase With Phosphate Bound In The Active Site. |
PDB | 1ygp_A | 0 | 15 | 818 | 40 | 876 | A Chain A, Phosphorylated Form Of Yeast Glycogen Phosphorylase With Phosphate Bound In The Active Site. |
PDB | 2qll_A | 0 | 14 | 827 | 23 | 834 | A Chain A, Human Liver Glycogen Phosphorylase- Gl Complex |
PDB | 1l7x_B | 0 | 14 | 827 | 23 | 834 | A Chain A, Human Liver Glycogen Phosphorylase- Gl Complex |
PDB | 1l7x_A | 0 | 14 | 827 | 23 | 834 | A Chain A, Human Liver Glycogen Phosphorylase- Gl Complex |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
starch degradation I | RXN-1826 | EC-2.4.1.1 | phosphorylase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO431119 | 516 | 308 | 823 | 0 |
HO424773 | 526 | 296 | 821 | 0 |
HO586252 | 556 | 279 | 824 | 0 |
DC936025 | 255 | 454 | 708 | 0 |
HO417459 | 283 | 432 | 714 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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