| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s194_131V6.1 |
| Family | GT21 |
| Protein Properties | Length: 580 Molecular Weight: 64910.7 Isoelectric Point: 6.9317 |
| Chromosome | Chromosome/Scaffold: 194 Start: 574293 End: 579273 |
| Description | Nucleotide-diphospho-sugar transferases superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT21 | 147 | 317 | 1.2e-28 |
| VSVVMPLKGFGEHNLSNWRSQVLSMYGGPLEFLFVVESKEDPACEVILQLMRDLKGEVDAKLLVAGYSTTCSQKIHNQLAGVDAMHKDSKYVLFLDDDVQ LCPGSIGALVAHMIEHPEIFVLTGYPFDLPSGSISSYCIYEYHLPCSIGFGFGRTFFLWGGCMMMHAEDFR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 580 Download |
| MCTKLLLLLR PRVIKIKTAH QSVPRTMDDD ETGPFQCVWS ESDGFHTATQ PLLQQQCARA 60 DHGGDAAMDA WLAWASLVFC HPVSIFLQLK GCLVYLVLAA GWAYNSVVRA RELHRIRAAE 120 AAGNALAFLY PNVDDLEHSA QAKLLRVSVV MPLKGFGEHN LSNWRSQVLS MYGGPLEFLF 180 VVESKEDPAC EVILQLMRDL KGEVDAKLLV AGYSTTCSQK IHNQLAGVDA MHKDSKYVLF 240 LDDDVQLCPG SIGALVAHMI EHPEIFVLTG YPFDLPSGSI SSYCIYEYHL PCSIGFGFGR 300 TFFLWGGCMM MHAEDFRTDR YGMVTGLREG GYSDDMTLAA VAGANQRVIS SPERAIFFHP 360 LAKDLSFSRY WNYLQKQTIV LETYNTTYNY WMNRGLFFLH CWASWSFVFP YLTSCVHLLV 420 AMRMLMGASA ELYSSWTTGL WLTGCIATAT LIELSSMRHL STVVIDLINA LSPGKDPVSI 480 SSYNYVKVFV AGIVGNFLYP VSAVYSHVFQ HIDWAGVQYW LGNGNICQIQ RGSRRWRVVE 540 SSKSGWSTEE IHGQFPNKST VWTLLSDLLM NQSCKLKNS* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam13641 | Glyco_tranf_2_3 | 0.005 | 146 | 317 | 179 | + Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. | ||
| pfam00535 | Glycos_transf_2 | 5.0e-5 | 220 | 317 | 102 | + Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids. | ||
| cd02520 | Glucosylceramide_synthase | 2.0e-7 | 147 | 372 | 232 | + Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. | ||
| COG1215 | COG1215 | 2.0e-8 | 146 | 506 | 379 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
| pfam13506 | Glyco_transf_21 | 2.0e-12 | 203 | 372 | 175 | + Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. | ||
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAK73021.1 | 0 | 66 | 535 | 3 | 477 | AF367245_1 ceramide glucosyltransferase [Gossypium arboreum] |
| GenBank | ABK95617.1 | 0 | 67 | 535 | 4 | 474 | unknown [Populus trichocarpa] |
| RefSeq | XP_001775646.1 | 0 | 67 | 530 | 6 | 470 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002329645.1 | 0 | 64 | 533 | 3 | 481 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002514215.1 | 0 | 67 | 535 | 9 | 479 | ceramide glucosyltransferase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| sphingolipid biosynthesis (plants) | RXN-7793 | EC-2.4.1.80 | ceramide glucosyltransferase |
