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Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s1_374V6.1 |
Family | GT47 |
Protein Properties | Length: 543 Molecular Weight: 61148.6 Isoelectric Point: 8.0416 |
Chromosome | Chromosome/Scaffold: 1 Start: 2289659 End: 2292332 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 108 | 483 | 0 |
SCKGRLVYVYNISEVYNREFVRECASFKKGRDLCMYMENLGMGRGFGFGVDHGGPVGGESEQGPWYNTWQFALELYFHERLLRHPCVTERKDLATAFFLP YYAGMDLSRRFTHRLAKDELYMNLGKWLQGRESWKLREGRDHFMVLGRIASDFHREGGDRDWGNRMLRQKAFKEMVVVAIEHTYGRFREGASIDNEIAIP YPTYFHASSDGEIQSLIAWLGQGLQRVSLATMAAGQRSPSTNKMRYRLMTQCGDDPRCTLLRCVGHESSSSLPDQIGNISSSMKLEGKTLDVPCNNPQVL LNAMHQSEFCLQPPGDSPTRRSFFDSMLVGCIPVIFHREAAWSQYVHHLPENGESYSVFIPMALAIKSNVLNILSE |
Full Sequence |
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Protein Sequence Length: 543 Download |
MKPVETGQFG HHRGDGSDHK CCSSSRSSCS NPRATLCPSS SASAIATRIS LLIVCAFTIF 60 LVFFCDDYTE HATTSRNVLL MHDHPASTRE QKPAELELQE NSAKLTSSCK GRLVYVYNIS 120 EVYNREFVRE CASFKKGRDL CMYMENLGMG RGFGFGVDHG GPVGGESEQG PWYNTWQFAL 180 ELYFHERLLR HPCVTERKDL ATAFFLPYYA GMDLSRRFTH RLAKDELYMN LGKWLQGRES 240 WKLREGRDHF MVLGRIASDF HREGGDRDWG NRMLRQKAFK EMVVVAIEHT YGRFREGASI 300 DNEIAIPYPT YFHASSDGEI QSLIAWLGQG LQRVSLATMA AGQRSPSTNK MRYRLMTQCG 360 DDPRCTLLRC VGHESSSSLP DQIGNISSSM KLEGKTLDVP CNNPQVLLNA MHQSEFCLQP 420 PGDSPTRRSF FDSMLVGCIP VIFHREAAWS QYVHHLPENG ESYSVFIPMA LAIKSNVLNI 480 LSEIKESKIK EMRANIAKLI PRILYARLSE SPTGKSNSAD QTLDAFDIAL DQVLKRITSR 540 QS* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-43 | 171 | 484 | 322 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_001150032.1 | 0 | 105 | 541 | 54 | 454 | xyloglucan galactosyltransferase KATAMARI 1 [Zea mays] |
RefSeq | NP_180834.1 | 0 | 72 | 537 | 50 | 474 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_001751530.1 | 0 | 81 | 542 | 1 | 445 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002321098.1 | 0 | 67 | 537 | 20 | 438 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518609.1 | 0 | 47 | 537 | 9 | 463 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
BJ180151 | 180 | 166 | 345 | 0 |
BJ166439 | 123 | 421 | 543 | 0 |
CF668912 | 323 | 226 | 542 | 0 |
EL456596 | 295 | 172 | 461 | 0 |
JG636298 | 296 | 187 | 477 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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