| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s1_376V6.1 |
| Family | CE11 |
| Protein Properties | Length: 364 Molecular Weight: 38933.5 Isoelectric Point: 8.5911 |
| Chromosome | Chromosome/Scaffold: 1 Start: 2298327 End: 2299947 |
| Description | UDP-3-O-acyl N-acetylglycosamine deacetylase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE11 | 67 | 351 | 0 |
| QQTIATTATRIGVGLHSGQGATVKLVPARANEGRYFVKLHRKEPAVIVPAIVNNTIDTRLSTCLGRNGSTVRTVEHLMSALEGLGVDNCRIEIEGGNEVP LLDGSAREWVEAIEESGLSIAKDYAGFGSARNAYVLDSPITVHQGDSFVAAFPSPFTRLTYGIDFPHVPAIGLRWFCWTPSGPSSYKHEVAPARTFGIAE QLEQLRAAGLIKGGSLDNALVCSTEEGWLNPPLRFDDEPCRHKLLDLIGDLALCAAPGHPGLPIAHIVAFKASHALHVKFGAALL | |||
| Full Sequence |
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| Protein Sequence Length: 364 Download |
| MYASRNRFPM VRGAAIPLLS AMPSMRSLSY LAAIAASSSL SSSSSSSQQI GRASSRVSHV 60 YRASQLQQTI ATTATRIGVG LHSGQGATVK LVPARANEGR YFVKLHRKEP AVIVPAIVNN 120 TIDTRLSTCL GRNGSTVRTV EHLMSALEGL GVDNCRIEIE GGNEVPLLDG SAREWVEAIE 180 ESGLSIAKDY AGFGSARNAY VLDSPITVHQ GDSFVAAFPS PFTRLTYGID FPHVPAIGLR 240 WFCWTPSGPS SYKHEVAPAR TFGIAEQLEQ LRAAGLIKGG SLDNALVCST EEGWLNPPLR 300 FDDEPCRHKL LDLIGDLALC AAPGHPGLPI AHIVAFKASH ALHVKFGAAL LQHQMKLHNL 360 VQV* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK13188 | PRK13188 | 8.0e-75 | 67 | 363 | 326 | + bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed | ||
| TIGR00325 | lpxC | 7.0e-92 | 67 | 354 | 291 | + UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]. | ||
| pfam03331 | LpxC | 4.0e-99 | 67 | 354 | 292 | + UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A. | ||
| COG0774 | LpxC | 3.0e-104 | 66 | 351 | 292 | + UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane] | ||
| PRK13186 | lpxC | 1.0e-125 | 67 | 354 | 289 | + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008759 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
| GO:0009245 | lipid A biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI26831.1 | 0 | 65 | 346 | 23 | 305 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001049426.1 | 0 | 55 | 346 | 13 | 302 | Os03g0223900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_001751532.1 | 0 | 25 | 363 | 1 | 339 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002315856.1 | 0 | 62 | 338 | 2 | 280 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002468246.1 | 0 | 67 | 346 | 26 | 306 | hypothetical protein SORBIDRAFT_01g042410 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3nzk_B | 1.99993e-41 | 67 | 354 | 9 | 284 | A Chain A, Structure Of Lpxc From Yersinia Enterocolitica Complexed With Chir090 Inhibitor |
| PDB | 3nzk_A | 1.99993e-41 | 67 | 354 | 9 | 284 | A Chain A, Structure Of Lpxc From Yersinia Enterocolitica Complexed With Chir090 Inhibitor |
| PDB | 4j3d_B | 7.00005e-41 | 67 | 343 | 4 | 267 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| PDB | 4j3d_A | 7.00005e-41 | 67 | 343 | 4 | 267 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| PDB | 3uhm_A | 8.00001e-41 | 67 | 343 | 4 | 267 | A Chain A, Pseudomonas Aeruginosa Lpxc In Complex With A Hydroxamate Inhibitor |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| lipid IVA biosynthesis | UDPACYLGLCNACDEACETYL-RXN | EC-3.5.1.108 | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CO485135 | 250 | 102 | 351 | 0 |
| BY964194 | 171 | 57 | 226 | 0 |
| HO453942 | 294 | 62 | 352 | 0 |
| GT006630 | 270 | 62 | 324 | 0 |
| CK277774 | 267 | 65 | 325 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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