Basic Information | |
---|---|
Species | Physcomitrella patens |
Cazyme ID | Pp1s20_115V6.1 |
Family | GT47 |
Protein Properties | Length: 530 Molecular Weight: 60101.6 Isoelectric Point: 6.7829 |
Chromosome | Chromosome/Scaffold: 20 Start: 683144 End: 684733 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 124 | 471 | 0 |
CDGRLIYIYNLAKEFNRLVVEQCSNWEAWPNMCEDISNQGFGVPLQVPASDPMASILQPPDAWFRTDQFTLEIVFHERLKVHPCLTKNSEEASLFYLPFY HGLDLAQNLYNSDLAVRDRLNELFVKWLRSQKPWQRHHGKRHVLVLGRIVWDFVRKIGKDASWGSSLLTQPELTNVTKLLIERSLWEDSMLGIPYPTAFH PSSESDLRAWQHTVRTFDRRQLVSLAGSTRTKKLTGVIRDEVFDQCTNSISCRTIFCNIERCVERPQIILKMGLESVFCLQPPGDSSTRKGVFDSLETGC IPVIFNKHQAPNQYLMHLPADHNDYSVLVPEEEVCNRTFDIMEHLSKI |
Full Sequence |
---|
Protein Sequence Length: 530 Download |
MSQWHIRVPK GGLRHSKPKP SSARWVISGI FTLSIIFLYM TARNEWISAV ENAMPISKVT 60 EPSDKNSLRF SPVPTDIEGS QQVNSSSAST DAELLEKPVI SAATSEVVSD IVDTTPKSDT 120 LDKCDGRLIY IYNLAKEFNR LVVEQCSNWE AWPNMCEDIS NQGFGVPLQV PASDPMASIL 180 QPPDAWFRTD QFTLEIVFHE RLKVHPCLTK NSEEASLFYL PFYHGLDLAQ NLYNSDLAVR 240 DRLNELFVKW LRSQKPWQRH HGKRHVLVLG RIVWDFVRKI GKDASWGSSL LTQPELTNVT 300 KLLIERSLWE DSMLGIPYPT AFHPSSESDL RAWQHTVRTF DRRQLVSLAG STRTKKLTGV 360 IRDEVFDQCT NSISCRTIFC NIERCVERPQ IILKMGLESV FCLQPPGDSS TRKGVFDSLE 420 TGCIPVIFNK HQAPNQYLMH LPADHNDYSV LVPEEEVCNR TFDIMEHLSK IPPSEIARKQ 480 KCIVDLIPRL LYRHPKPVGE YTSRDAFDVA MDGLMARFDA EQANSGAQL* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-45 | 123 | 457 | 347 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001752322.1 | 0 | 3 | 526 | 6 | 525 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001755886.1 | 0 | 122 | 515 | 1 | 394 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001785740.1 | 0 | 124 | 515 | 1 | 392 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001785839.1 | 0 | 124 | 511 | 8 | 387 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002442366.1 | 0 | 122 | 517 | 172 | 557 | hypothetical protein SORBIDRAFT_08g018880 [Sorghum bicolor] |