| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s21_151V6.1 |
| Family | GT28 |
| Protein Properties | Length: 441 Molecular Weight: 47495.5 Isoelectric Point: 9.709 |
| Chromosome | Chromosome/Scaffold: 21 Start: 1090725 End: 1092643 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT28 | 267 | 427 | 0 |
| VVVMGGSLGARIINETMAEIASSLLEQKRGRYIIWQTGTINYDSTMRRVGSHPRLALLPYVDAMEMMYAAADIVVARAGAITCSELLVTATPAILIPATS VAEDHQMKNARAMAEGGAATILPERDLVAERLATVILNILGDNAEQRRMQNAALRMAAPDA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 441 Download |
| MTLLSRASFG SLRFAPERGA ECSSLCVSFQ ARKQGGSAIL MSWPLVLKLR SRGVCASVGN 60 ENSGETVRAG PRIMFAAGGT GGHVYPALAI ADEVKMLNPA AEIEFVGTIE RMEWVAVPKA 120 GFPISPIPAV AIRRPFWSLA NVLLPFRLLL CLWMSWRIVR KFRPDVVVGT GGYVAGPLCL 180 MAALAGTAVA IQEQNAYAGV TNRILGRVAK VIFIAFAAAT SYFPKQKCVF IGNPTRRVLQ 240 QRIDRLSALR YFFGDLNVDG HEDLEVVVVM GGSLGARIIN ETMAEIASSL LEQKRGRYII 300 WQTGTINYDS TMRRVGSHPR LALLPYVDAM EMMYAAADIV VARAGAITCS ELLVTATPAI 360 LIPATSVAED HQMKNARAMA EGGAATILPE RDLVAERLAT VILNILGDNA EQRRMQNAAL 420 RMAAPDAAQQ LAKHVLSLAS * |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK12446 | PRK12446 | 3.0e-30 | 72 | 435 | 369 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed | ||
| TIGR01133 | murG | 2.0e-70 | 72 | 433 | 363 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| COG0707 | MurG | 1.0e-78 | 72 | 439 | 368 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| PRK00726 | murG | 9.0e-105 | 71 | 439 | 369 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| cd03785 | GT1_MurG | 6.0e-112 | 72 | 434 | 364 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030246 | carbohydrate binding |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAH23791.1 | 0 | 41 | 440 | 1 | 400 | MurG transferase [Physcomitrella patens] |
| EMBL | CBI15500.1 | 0 | 40 | 438 | 23 | 428 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_001756202.1 | 0 | 74 | 440 | 1 | 367 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002277203.1 | 0 | 48 | 438 | 31 | 423 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002524882.1 | 0 | 48 | 438 | 34 | 429 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s2u_A | 0 | 73 | 439 | 5 | 355 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_B | 5.04467e-44 | 70 | 439 | 6 | 354 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_A | 5.04467e-44 | 70 | 439 | 6 | 354 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1f0k_B | 5.04467e-44 | 70 | 439 | 6 | 354 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 5.04467e-44 | 70 | 439 | 6 | 354 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
