Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s236_30V6.1 |
Family | GT47 |
Protein Properties | Length: 644 Molecular Weight: 72332 Isoelectric Point: 8.2103 |
Chromosome | Chromosome/Scaffold: 236 Start: 253815 End: 256434 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 234 | 584 | 0 |
SCKGRYIYVYDLPSEFNVDLVKRCDSLLPWFGLCEYFQNSGFGRVVAPEGGKNDSSQILQPAKRWFNTHQYSLELVSHARILKYRCRTDDQSKASLFYIP YYGGLDVIRWHWALNATNEKRDALGRKLVRWLENQPSWNRRGGLDHVLVLGKISWDFRRQITGDWGSRLLEFSEMQKVTKLLIERNPWHKNDIGVPHPTF FHPKSASDIRRWLTHVESQDRKNLASFVGKDRHLDPNNVRGALIDQCRNASAHNDCFFLECERDKCLLPAYVTRVFLTSHFCMQPPGDSPTRRSVFDSLV AGCIPVLFHPCTAYLQYPWHLPSNTSSWSVYISENDVKSGKVNVMDVLKKI |
Full Sequence |
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Protein Sequence Length: 644 Download |
MGDKNAPQGL AHKVFSARHR AKLLLPFCLL VVGIVWSSSS LIPFSSMPGS RVYLRQCATC 60 APEAVLSGDN LEEVGGSTTL QLKESLNVQD GRHPQADTRS QLAAGKNSKA GDARSGKNAA 120 LAGKKPRKTL VPDLALSATV ETEDSPLGRK SFSKEDDEED TQPDKPVEME EMDILRTELS 180 AALMQSEKRA HGGDTRITGD LYANGDRYAL RILDEIRSNS APPSENSSST DGGSCKGRYI 240 YVYDLPSEFN VDLVKRCDSL LPWFGLCEYF QNSGFGRVVA PEGGKNDSSQ ILQPAKRWFN 300 THQYSLELVS HARILKYRCR TDDQSKASLF YIPYYGGLDV IRWHWALNAT NEKRDALGRK 360 LVRWLENQPS WNRRGGLDHV LVLGKISWDF RRQITGDWGS RLLEFSEMQK VTKLLIERNP 420 WHKNDIGVPH PTFFHPKSAS DIRRWLTHVE SQDRKNLASF VGKDRHLDPN NVRGALIDQC 480 RNASAHNDCF FLECERDKCL LPAYVTRVFL TSHFCMQPPG DSPTRRSVFD SLVAGCIPVL 540 FHPCTAYLQY PWHLPSNTSS WSVYISENDV KSGKVNVMDV LKKISKHDRD AMRRVILKDI 600 IPKIIYGEPG ADIAPFKDAF DIVLENLLYR AAHSPDLEQL SQN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-59 | 234 | 584 | 366 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | XP_001756054.1 | 0 | 234 | 636 | 1 | 400 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001757088.1 | 0 | 210 | 638 | 1 | 426 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001759310.1 | 0 | 234 | 628 | 1 | 392 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001778302.1 | 0 | 207 | 628 | 1 | 410 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002299537.1 | 0 | 229 | 632 | 181 | 570 | predicted protein [Populus trichocarpa] |