Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s242_74V6.1 |
Family | GT64 |
Protein Properties | Length: 895 Molecular Weight: 102592 Isoelectric Point: 6.994 |
Chromosome | Chromosome/Scaffold: 242 Start: 494815 End: 497823 |
Description | Nucleotide-diphospho-sugar transferases superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT64 | 53 | 299 | 0 |
TILVNGFGEARLPLLEASVRKYSSSPVVHSVFVLWGNTSTPDSFLQASKFQSIGAPIYIVRQNSMSLNDRFLPRPFVKTKAVMICDDDITVDSKNLEFAL QVWRENQQRIVGFFPRAHSYQLDSHSWVYTKNQHHYSIVLTKIMILATDYLYRYSCEMPAGVRDYVDKGMNCEDIAMNFLVSNFSGSGPLLVEGQPRDWG DTRNSKEDLTTMSLSARAGHRKDRGDCIMEFQRLWNGMELRFSHAKA |
Full Sequence |
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Protein Sequence Length: 895 Download |
MGLWLALESS QKDGYEPSTF KSITRRMSAE LGDDVCDRKL YPPPWELRTD QLTILVNGFG 60 EARLPLLEAS VRKYSSSPVV HSVFVLWGNT STPDSFLQAS KFQSIGAPIY IVRQNSMSLN 120 DRFLPRPFVK TKAVMICDDD ITVDSKNLEF ALQVWRENQQ RIVGFFPRAH SYQLDSHSWV 180 YTKNQHHYSI VLTKIMILAT DYLYRYSCEM PAGVRDYVDK GMNCEDIAMN FLVSNFSGSG 240 PLLVEGQPRD WGDTRNSKED LTTMSLSARA GHRKDRGDCI MEFQRLWNGM ELRFSHAKAV 300 RDVDEQVNCE KFGLLIDCDK SVGSARDAHR LAGHNLVKRT YQYAYATFIQ SKVMYYAALV 360 WAQALRNTGT VHDLVLLLDI NSGLKKDNEL LADHFDVVKE VRAFRTRHKT RSVGRLSVWE 420 LLEYERVVYM DVNLLCLSNL DYLFELPEPA AAPLTNHPLQ FDTGLLVLQP SNATFTDLFN 480 WIEGVSSPDR RTEHRLLNGF FHDWFHMSSK HRLPMYLNMP VHLASFASVF GNWSESEAAA 540 PLLGALQFSK RKIASFLSVW IKEEVNSELN QTLGFRYREE AQYRTDWFGI WLEILDALRS 600 NNYQPLSDEV VSQLSWKQRK GSSTWPPKSL MAALPSPFQH LHVPPLRKAF ATVVTSIDQL 660 VAIAGWMITY SKFHMPTAEY ESVLLVHGSV GEKTWRPFRT LFSSVVVVNG SNSSSSVETM 720 SATMLQLWNL TKYDKLVYVD PRSIFLSNCD FLMEFEPFAA APDFIFPDTF SLQVMVLQPD 780 NHRFLELWKS LSNEISEDFS LTRFLNEHHS SWYQFSTKHR IEPISNAQNE LERGFKADGS 840 LKILSLHSTT TLSDSNSEIA GIWRKHVCSS LHMRNFGFRI SLHDICNPMD YKFQ* 900 |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
cd06914 | GT8_GNT1 | 0.006 | 721 | 796 | 79 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. |
cd06914 | GT8_GNT1 | 8.0e-8 | 343 | 482 | 152 | + GNT1 is a fungal enzyme that belongs to the GT 8 family. N-acetylglucosaminyltransferase is a fungal enzyme that catalyzes the addition of N-acetyl-D-glucosamine to mannotetraose side chains by an alpha 1-2 linkage during the synthesis of mannan. The N-acetyl-D-glucosamine moiety in mannan plays a role in the attachment of mannan to asparagine residues in proteins. The mannotetraose and its N-acetyl-D-glucosamine derivative side chains of mannan are the principle immunochemical determinants on the cell surface. N-acetylglucosaminyltransferase is a member of glycosyltransferase family 8, which are, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed, retaining glycosyltransferases. |
cd02537 | GT8_Glycogenin | 7.0e-14 | 723 | 827 | 106 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. |
cd02537 | GT8_Glycogenin | 1.0e-25 | 343 | 528 | 197 | + Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases. |
pfam09258 | Glyco_transf_64 | 3.0e-71 | 52 | 302 | 252 | + Glycosyl transferase family 64 domain. Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate. |
Gene Ontology | |
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GO Term | Description |
GO:0016757 | transferase activity, transferring glycosyl groups |
GO:0016758 | transferase activity, transferring hexosyl groups |
GO:0031227 | intrinsic to endoplasmic reticulum membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68561.1 | 0 | 31 | 320 | 24 | 326 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_001778641.1 | 0 | 27 | 307 | 1 | 281 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002280907.1 | 0 | 31 | 320 | 24 | 326 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002330776.1 | 0 | 36 | 320 | 26 | 331 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523753.1 | 0 | 44 | 320 | 49 | 347 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1on8_B | 6e-23 | 38 | 296 | 16 | 276 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |
PDB | 1on8_A | 6e-23 | 38 | 296 | 16 | 276 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |
PDB | 1on6_B | 6e-23 | 38 | 296 | 16 | 276 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |
PDB | 1on6_A | 6e-23 | 38 | 296 | 16 | 276 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |
PDB | 1omz_B | 6e-23 | 38 | 296 | 16 | 276 | A Chain A, The Structure Of A Protein In Glycosyl Transferase Family 8 From Anaerococcus Prevotii. |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO593681 | 220 | 107 | 326 | 0 |
HO590615 | 208 | 107 | 314 | 0 |
DR047906 | 211 | 35 | 243 | 0 |
DR546358 | 223 | 113 | 332 | 0 |
EL480538 | 265 | 74 | 320 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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