| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s245_59V6.1 |
| Family | GT1 |
| Protein Properties | Length: 871 Molecular Weight: 94705.1 Isoelectric Point: 7.058 |
| Chromosome | Chromosome/Scaffold: 245 Start: 265110 End: 273550 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GT1 | 423 | 832 | 0 |
| VGTRGDVQPFIAIGRKLQEHGHRVRLASHKNFEGFVKSGGLEFYPLGGDPVVLAGYMVKNKGFLPSNPAEIPVQRQQIKSIVHSLLPACTQPDLASGIPF QAQAIIANPPAYGHVHVAEFLKIPLHIFFTMPWTPTSAFPHPLSRVKQPAGYRMSYQIVDTMIWLGIRGIINSYRKKKLKLRPITYFSGSHGSIAEMPTG YIWSPHLVPKPRDWGSSVDVVGFCFLNLATDYKPPEDLVNWLKAGSPPIYIGFGSLPVEDPEGMTKIIVEALNKTGQRGIIGKGWGGIGNLPETPENIFL LSDCPHDWLFPQCAGVIHHGGAGTTSAGLKAACPTTIIPFFGDQPFWGDRVHEKGVGPAPIPVNHLTLERLVNAIEKMLDPVVKQAALDLSKAMENEDGV EGAVNAFHKH | |||
| Full Sequence |
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| Protein Sequence Length: 871 Download |
| MSVIGDSQPI ALHLHTSSNM LHDSTLRTPQ PSRSEMTTTS RITQGLHHSS DAASPSNSLS 60 SASQLRTIPD NFESNQSTLQ YLPAGTPSAS TSENDFVTCT TDIPLLTTFP AAVPPSLLAD 120 LASSSQQCTD KDGESSGLDV VSVLLSEDSG IESQSLESMK ALVTDSALST SVLQNATEFR 180 TSSLGEGRAN VVVCRVDGKA NTSLVGSNPH TADLKGENGL GQEDGQPLHD NLSVPASMPS 240 SDSTLISGNG SGDLSPVGDM STSEHEMKVL KDSSVHLLQN IFENAEDVAS DEAVGRTKSM 300 PAPKSESVHS ARFLRRSSTE KRRRGMNTDN VNVRVTPEFN KLSDRRKKKL LRKLATIKKD 360 GVVEFDVGDS SQAAKDLFGY GFSPVGDAKY ENDDDGQDEK TTQEEYLNNF KSVPPLRIVM 420 LIVGTRGDVQ PFIAIGRKLQ EHGHRVRLAS HKNFEGFVKS GGLEFYPLGG DPVVLAGYMV 480 KNKGFLPSNP AEIPVQRQQI KSIVHSLLPA CTQPDLASGI PFQAQAIIAN PPAYGHVHVA 540 EFLKIPLHIF FTMPWTPTSA FPHPLSRVKQ PAGYRMSYQI VDTMIWLGIR GIINSYRKKK 600 LKLRPITYFS GSHGSIAEMP TGYIWSPHLV PKPRDWGSSV DVVGFCFLNL ATDYKPPEDL 660 VNWLKAGSPP IYIGFGSLPV EDPEGMTKII VEALNKTGQR GIIGKGWGGI GNLPETPENI 720 FLLSDCPHDW LFPQCAGVIH HGGAGTTSAG LKAACPTTII PFFGDQPFWG DRVHEKGVGP 780 APIPVNHLTL ERLVNAIEKM LDPVVKQAAL DLSKAMENED GVEGAVNAFH KHIRHRIPQT 840 VSSREFHRPS RRYSYRRALF KWTTSCLQVY * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 8.0e-9 | 421 | 802 | 397 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| pfam03033 | Glyco_transf_28 | 7.0e-32 | 418 | 562 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| COG1819 | COG1819 | 3.0e-46 | 417 | 840 | 441 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| cd03784 | GT1_Gtf_like | 2.0e-127 | 417 | 832 | 416 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
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| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC22617.1 | 0 | 310 | 836 | 69 | 580 | UDP-glucose:sterol 3-O-glucosyltransferase [Panax ginseng] |
| EMBL | CBI37267.1 | 0 | 314 | 836 | 83 | 592 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_001769124.1 | 0 | 349 | 842 | 1 | 491 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001778784.1 | 0 | 337 | 870 | 8 | 541 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001780556.1 | 0 | 349 | 870 | 1 | 516 | predicted protein [Physcomitrella patens subsp. patens] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 4e-27 | 418 | 819 | 3 | 368 | A Chain A, Structure And Mechanisim Of Core 2 Beta1,6-N- Acetylglucosaminyltransferase: A Metal-Ion Independent Gt-A Glycosyltransferase |
| PDB | 3h4i_A | 4e-27 | 418 | 819 | 3 | 368 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 1e-24 | 416 | 845 | 1 | 409 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1rrv_B | 5e-24 | 416 | 809 | 1 | 376 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 5e-24 | 416 | 809 | 1 | 376 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| GT046352 | 335 | 425 | 759 | 0 |
| HO626576 | 427 | 411 | 833 | 0 |
| HO801427 | 395 | 445 | 832 | 0 |
| HO801427 | 29 | 416 | 444 | 0.0003 |
| GT046352 | 32 | 752 | 783 | 0.001 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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