| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s2609_1V6.1 |
| Family | GH18 |
| Protein Properties | Length: 765 Molecular Weight: 84578.8 Isoelectric Point: 7.8971 |
| Chromosome | Chromosome/Scaffold: 2609 Start: 58 End: 3267 |
| Description | |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH18 | 1 | 130 | 2.1e-21 |
| MGYDEHWGGDPIAGSVSSYPWVESALDKLLRSVPSSKTILALPFYTRDWTLKEGGATSEELNLAQQGVRTRSVAYNRSWDDNLGQYVFKYQKQGYTHKIW IEDSRSITKKYVMAADRGVAGYAFWYMGAE | |||
| Full Sequence |
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| Protein Sequence Length: 765 Download |
| MGYDEHWGGD PIAGSVSSYP WVESALDKLL RSVPSSKTIL ALPFYTRDWT LKEGGATSEE 60 LNLAQQGVRT RSVAYNRSWD DNLGQYVFKY QKQGYTHKIW IEDSRSITKK YVMAADRGVA 120 GYAFWYMGAE TPDVWTAMSN AARFWNSPVS ILWNFGRRIG MNLLDLSFKR TSYEAKVLSS 180 IWYECALGAA VLTYPKLHGS LDKPGEYYAQ LRQRASSRLE AELQFCQEHN TWKMLLQLLH 240 FLNCETIESF AMEAHALSRE EFRFLVLPYL ETALEPARRR AAEGDAAGAE EMMGACRGHR 300 FFPQLIHDVM TTDADTLRDH LIALLQLWDA EFMEREREIT AASPEQSEGD YAQLRRWPQN 360 FAWLYADQLL SVFAGTCGTF ILSWLLYEVT GSTVAMGGLW LISFASQWGV QLLAGPLIDR 420 WKRTAVMKLS EAVRAAVYLA AGLMWIAGER QSYILYTASW ISSFVMYDLA SGALLPKLVR 480 PEELTRKNAW MSGSVQLMRT LAFPLAGFGV QVLESGALLL IMSLLFAGSF LCICCIREGP 540 PAYAASPEQG RSGAGAAWFG QVRAGWKVFS GNRLLVALAL FVSVTSFGVA ATQAMYIPYV 600 SEVLGGGAAE YGWFTAAFPC GYVLGSWAAG RIRGTSPMLG TMLTALLTGG ATYVGLSLVR 660 SLPAALVIEL AAGIAMPFWN VFSSNAFYRL VPEQVLGQVL SMRLLLVKSA GPLGILYGTF 720 CAAAYGIPRL FLTVGLLIMA VTGIGVVWTM IFRHNPAGEL RKYP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07690 | MFS_1 | 5.0e-10 | 368 | 714 | 353 | + Major Facilitator Superfamily. | ||
| cd06549 | GH18_trifunctional | 3.0e-13 | 1 | 135 | 136 | + GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain. | ||
| COG3858 | COG3858 | 1.0e-19 | 1 | 140 | 143 | + Predicted glycosyl hydrolase [General function prediction only] | ||
| cd02874 | GH18_CFLE_spore_hydrolase | 2.0e-24 | 1 | 138 | 141 | + Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. | ||
| TIGR00900 | 2A0121 | 2.0e-28 | 361 | 726 | 371 | + H+ Antiporter protein. [Transport and binding proteins, Cations and iron carrying compounds]. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016021 | integral to membrane |
| GO:0055085 | transmembrane transport |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001786553.1 | 0 | 1 | 764 | 1 | 764 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | ZP_03234808.1 | 2.99878e-43 | 359 | 747 | 10 | 390 | putative permease [Bacillus cereus H3081.97] |
| RefSeq | ZP_04169421.1 | 8.99634e-43 | 370 | 727 | 7 | 356 | Multidrug-efflux transporter [Bacillus mycoides DSM 2048] |
| RefSeq | ZP_04257294.1 | 8.00001e-42 | 359 | 727 | 10 | 370 | Multidrug-efflux transporter [Bacillus cereus BDRD-Cer4] |
| RefSeq | ZP_04262687.1 | 2.99878e-43 | 359 | 727 | 8 | 368 | Multidrug-efflux transporter [Bacillus cereus BDRD-ST196] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3cz8_B | 0.00007 | 1 | 110 | 181 | 291 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| PDB | 3cz8_A | 0.00007 | 1 | 110 | 181 | 291 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
