Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s269_93V6.1 |
Family | GT4 |
Protein Properties | Length: 472 Molecular Weight: 52288.6 Isoelectric Point: 8.7858 |
Chromosome | Chromosome/Scaffold: 269 Start: 590439 End: 593995 |
Description | UDP-Glycosyltransferase superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT4 | 266 | 424 | 3.9e-27 |
PQKQYIISVAQFRPEKAHDLQLEAFALALEQLSLQNMEARLKLVGSCRNQEDENRVDSLKQRCQDLGLEQNVDFCLNVHYSELVKLLGGAIAGLHTMTDE HFGIVVVEYMAAGAVPIAHNSAGPKLDIVVNEGGHRTGFLASSVSEFADAMCHVVTLPA |
Full Sequence |
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Protein Sequence Length: 472 Download |
MQLLRLLPSA LFGAALLCAV VFLKTVLRAR RSVKPVVAFF HPYTNDGGGG ERVLWCAARA 60 VQEMAPALDI VVYTGDSATP ESLAARALDR FGVRLVKAPL VVKLDKRKWV ESKTYPRFTI 120 IGQSLGSMVL AWEALSKVTP LIFLDTSGYA FTYVFARAAG SLVVCYTHYP TISTDMLNRV 180 RDRTALYNND IRISRSFLLS MAKVWYYRAL AQLYGLAGRC AHLAMVNSSW TRAHINAIWR 240 IPNRTVLVYP PCDTLTLQAL PLERLPQKQY IISVAQFRPE KAHDLQLEAF ALALEQLSLQ 300 NMEARLKLVG SCRNQEDENR VDSLKQRCQD LGLEQNVDFC LNVHYSELVK LLGGAIAGLH 360 TMTDEHFGIV VVEYMAAGAV PIAHNSAGPK LDIVVNEGGH RTGFLASSVS EFADAMCHVV 420 TLPANERMEI AQAARVRAAL FSESEFDSAF KKAMNPLIEQ AFRFACNAES R* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd03801 | GT1_YqgM_like | 2.0e-17 | 205 | 439 | 244 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
cd03805 | GT1_ALG2_like | 1.0e-17 | 219 | 450 | 247 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
COG0438 | RfaG | 1.0e-17 | 184 | 460 | 279 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
PLN02949 | PLN02949 | 0 | 2 | 463 | 463 | + transferase, transferring glycosyl groups | ||
cd03806 | GT1_ALG11_like | 0 | 36 | 447 | 416 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. |
Gene Ontology | |
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GO Term | Description |
GO:0009058 | biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABA99697.1 | 0 | 35 | 458 | 30 | 454 | glycosyl transferase, group 1 family protein, expressed [Oryza sativa (japonica cultivar-group)] |
RefSeq | NP_181548.2 | 0 | 29 | 458 | 28 | 458 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
RefSeq | XP_001780017.1 | 0 | 1 | 471 | 1 | 472 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002318120.1 | 0 | 24 | 463 | 26 | 466 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528312.1 | 0 | 26 | 463 | 27 | 465 | glycosyl transferase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2f9f_A | 0.00000007 | 269 | 435 | 24 | 175 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
PDB | 3fro_C | 0.00002 | 278 | 464 | 262 | 437 | A Chain A, Crystal Structure Of Pyrococcus Abyssi Glycogen Synthase With Open And Closed Conformations |
PDB | 3fro_B | 0.00002 | 278 | 464 | 262 | 437 | A Chain A, Crystal Structure Of Pyrococcus Abyssi Glycogen Synthase With Open And Closed Conformations |
PDB | 3fro_A | 0.00002 | 278 | 464 | 262 | 437 | A Chain A, Crystal Structure Of Pyrococcus Abyssi Glycogen Synthase With Open And Closed Conformations |
PDB | 2bis_C | 0.00002 | 278 | 464 | 263 | 438 | A Chain A, Structure Of Glycogen Synthase From Pyrococcus Abyssi |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
dolichyl-diphosphooligosaccharide biosynthesis | RXN-5464 | EC-2.4.1.131 | GDP-Man:Man3GlcNAc2-PP-Dol α-1,2-mannosyltransferase |