Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s287_72V6.1 |
Family | GH19 |
Protein Properties | Length: 238 Molecular Weight: 25891.2 Isoelectric Point: 7.6862 |
Chromosome | Chromosome/Scaffold: 287 Start: 556615 End: 557726 |
Description | Chitinase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH19 | 36 | 237 | 0 |
TKAAFDQTYFPGHIAFYTYDSLKAAAGAPFTQFGNSGTLDDQKRELAAFFAQVKHESGGLKQKYEQGCNIQCQQSYCASSPTYPCSKTQPPYYFGRGPIQ LSWNYNYGACGDYIGKPLLREPSQISNSAVTAFQTALWFWMTQGPHLAKSFSGTTKAINGDIECKGGAHYSEKGHEQMLSRVQYYKSFCSVLGVDPGTDL EC |
Full Sequence |
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Protein Sequence Length: 238 Download |
MTGCDLHRPM VALVAVAALV LSLVQGASAA WSTFITKAAF DQTYFPGHIA FYTYDSLKAA 60 AGAPFTQFGN SGTLDDQKRE LAAFFAQVKH ESGGLKQKYE QGCNIQCQQS YCASSPTYPC 120 SKTQPPYYFG RGPIQLSWNY NYGACGDYIG KPLLREPSQI SNSAVTAFQT ALWFWMTQGP 180 HLAKSFSGTT KAINGDIECK GGAHYSEKGH EQMLSRVQYY KSFCSVLGVD PGTDLEC* 240 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00442 | lysozyme_like | 4.0e-5 | 82 | 191 | 111 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
COG3179 | COG3179 | 2.0e-9 | 76 | 195 | 157 | + Predicted chitinase [General function prediction only] | ||
pfam00182 | Glyco_hydro_19 | 3.0e-57 | 34 | 237 | 242 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 3.0e-63 | 51 | 237 | 217 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. |
Gene Ontology | |
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GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAF99002.1 | 0 | 25 | 237 | 19 | 228 | chitinase A [Bryum coronatum] |
RefSeq | XP_001762531.1 | 0 | 16 | 237 | 1 | 208 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001774954.1 | 0 | 27 | 237 | 85 | 288 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001780834.1 | 0 | 51 | 237 | 1 | 178 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001781688.1 | 4.2039e-45 | 34 | 237 | 77 | 296 | predicted protein [Physcomitrella patens subsp. patens] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3hbh_A | 0 | 50 | 237 | 26 | 204 | A Chain A, Backbone Structure Of The Membrane Domain Of E. Coli Histidine Kinase Receptor Kdpd, Center For Structures Of Membrane Proteins (Csmp) Target 4312c |
PDB | 3hbe_X | 0 | 50 | 237 | 26 | 204 | A Chain A, Backbone Structure Of The Membrane Domain Of E. Coli Histidine Kinase Receptor Kdpd, Center For Structures Of Membrane Proteins (Csmp) Target 4312c |
PDB | 3hbd_A | 0 | 50 | 237 | 26 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
PDB | 2cjl_B | 7.00649e-43 | 35 | 237 | 3 | 204 | A Chain A, Crystal Structure And Enzymatic Properties Of A Bacterial Family 19 Chitinase Reveal Differences With Plant Enzymes |
PDB | 2cjl_A | 7.00649e-43 | 35 | 237 | 3 | 204 | A Chain A, Crystal Structure And Enzymatic Properties Of A Bacterial Family 19 Chitinase Reveal Differences With Plant Enzymes |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |