Basic Information | |
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Species | Physcomitrella patens |
Cazyme ID | Pp1s309_76V6.1 |
Family | GT47 |
Protein Properties | Length: 677 Molecular Weight: 76115.7 Isoelectric Point: 6.5143 |
Chromosome | Chromosome/Scaffold: 309 Start: 426078 End: 428492 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 330 | 617 | 0 |
EKVFKVYIYKDGRKPLVHSGPQLGIYASEGQFIERMEAASEFLTDDPSRAHMFFLPYSVYRMVTHLYVPNSRSMLPLATFIKDYVEALARQYPYWNRTKG ADHFFVSCHDWGPATARDHPTLRSNAVKVVCNADLTEEFVVGKDASLPEVYMHKSKTKAPIKLGGPGYDERPYLAFFAGQMHGRVRPILLDHWKDKDPDL MIYGVLPKPIAKQISYVQHMKMSKYCICAAGYEVNSPRIVESIHYDCVPVIIADNFVLPFSDVLNWDAFSVTMPESDIPKLKAILNDI |
Full Sequence |
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Protein Sequence Length: 677 Download |
MARPRRCLGE RAHPTFLTSV VIAVSAIVLL QHICTTKGPA YSLLHSSLIS RQAEPVLSKL 60 DALTPTKGRH QKNLTPSSPE MISETENVST QAQSLSSNKR QDFSENFLHA GNESQMFTAV 120 ESEVSETGKE FNNNGTDLLV PETSNRQVSS EILNNGTMVE SVVAEAATER QVVAVETEAV 180 QIVKGVINSI NSSENMAEVA DRMDLDHNRS ELTVPNAESD SKGAIPVGGD EAVDVMQPRR 240 FESLGDANVG RIPVETETSH EENKQQLMIA SWPPQASPVP KVSKFNPIFD ELQTCKKAIE 300 GATLETADPS LDSSLYKNVT AFSKSYELME KVFKVYIYKD GRKPLVHSGP QLGIYASEGQ 360 FIERMEAASE FLTDDPSRAH MFFLPYSVYR MVTHLYVPNS RSMLPLATFI KDYVEALARQ 420 YPYWNRTKGA DHFFVSCHDW GPATARDHPT LRSNAVKVVC NADLTEEFVV GKDASLPEVY 480 MHKSKTKAPI KLGGPGYDER PYLAFFAGQM HGRVRPILLD HWKDKDPDLM IYGVLPKPIA 540 KQISYVQHMK MSKYCICAAG YEVNSPRIVE SIHYDCVPVI IADNFVLPFS DVLNWDAFSV 600 TMPESDIPKL KAILNDIPEK TYRSMQIRLR KIRQHFVWHK KPEKYDVFHM ILHSVWMSRI 660 NRLEQIRDLS EEPFKD* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-59 | 329 | 617 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | EEC69788.1 | 0 | 290 | 664 | 160 | 534 | hypothetical protein OsI_00072 [Oryza sativa Indica Group] |
RefSeq | NP_001041784.1 | 0 | 290 | 664 | 174 | 548 | Os01g0107700 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_001781686.1 | 0 | 1 | 323 | 1 | 323 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_001781687.1 | 0 | 324 | 676 | 24 | 376 | predicted protein [Physcomitrella patens subsp. patens] |
RefSeq | XP_002457517.1 | 0 | 290 | 664 | 147 | 521 | hypothetical protein SORBIDRAFT_03g008610 [Sorghum bicolor] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |