| Basic Information | |
|---|---|
| Species | Physcomitrella patens |
| Cazyme ID | Pp1s315_20V6.1 |
| Family | GT47 |
| Protein Properties | Length: 492 Molecular Weight: 56854.8 Isoelectric Point: 9.8402 |
| Chromosome | Chromosome/Scaffold: 315 Start: 105187 End: 107940 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 138 | 436 | 0 |
| NGIRVYVYDLPQKFNKDWLVDERCSNHLFASEVAIHKILLSSPIKTLNPYEADFFFMPVYFSCKFSSKTGFPRLGHAPKLMEDAVNHVSSMMEFWNRSGG KDHVFVAAHDFGACFHSLESEAIAHGIPEIVQSSLILQTFGVHGFHPCQAAENIQIPPYISPSTVFSYVKKPPEEQRRNIFAFFRGKMEINPKNVSGLVY SRGVRTYIYKKFSRNRRFFLKRHRADNYQLDLLRSTFCLCPLGWAPWSPRIVEAVAYGCVPVIIADNIRLPYSHAIDWSNMSLNIREHDVHKLYKILLN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 492 Download |
| MHRVSVVEWK GNGHRGIVSY GTVTSFSKHY KHEATAMSHS FWKKRRSIWL SICILFTVFV 60 LCVSVLPAPM DVSENLETGP LELLRKGLPI EKKSYVLHER MDGLEKSRKE WQLKPDHFTF 120 YNTLRNVPTP FNPLNLTNGI RVYVYDLPQK FNKDWLVDER CSNHLFASEV AIHKILLSSP 180 IKTLNPYEAD FFFMPVYFSC KFSSKTGFPR LGHAPKLMED AVNHVSSMME FWNRSGGKDH 240 VFVAAHDFGA CFHSLESEAI AHGIPEIVQS SLILQTFGVH GFHPCQAAEN IQIPPYISPS 300 TVFSYVKKPP EEQRRNIFAF FRGKMEINPK NVSGLVYSRG VRTYIYKKFS RNRRFFLKRH 360 RADNYQLDLL RSTFCLCPLG WAPWSPRIVE AVAYGCVPVI IADNIRLPYS HAIDWSNMSL 420 NIREHDVHKL YKILLNVAAK NLSSIQKNLW KEENRRVLLF MEPLAKGDAT WHMLDRLSTK 480 VDRSFVKHEN F* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 2.0e-69 | 136 | 434 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33322.1 | 0 | 119 | 485 | 72 | 434 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| GenBank | ABI64067.1 | 0 | 119 | 485 | 72 | 434 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
| RefSeq | XP_001754437.1 | 0 | 136 | 488 | 1 | 353 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001777222.1 | 0 | 129 | 488 | 9 | 368 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_001781950.1 | 0 | 136 | 491 | 1 | 356 | predicted protein [Physcomitrella patens subsp. patens] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
